Full story: https://www.sciencedaily.com/releases/2016/06/160630144409.htmTreating autoimmune disease without harming normal immunity
Preclinical study shows that engineered T cells can selectively target the antibody-producing cells that cause autoimmune disease
June 30, 2016
University of Pennsylvania School of Medicine
With potentially major implications for the future treatment of autoimmunity and related conditions, scientists have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system. They studied an autoimmune disease called pemphigus vulgaris, a condition in which a patient's own immune cells attack a protein called desmoglein-3 that normally adheres skin cells.