Sorry to hear mate, i seem to have somewhat similar experience of the 45 mins of help then stuff gets weird.
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What dose did you start with? I started with (and still take the same dose) 0.15mL = 450mcg TA1 everyday. This is much lower than the dose for ZADAXIN, which is 1600mcg but taken 2x/week. Others have needed a smaller starting dose for TA1 but I don't know what dosages they used or reduced to.First dose didn't go that well. Felt great for 45 minutes, then my cells started to do this thing where they slowly crash. By the time late evening rolled around I was feeling very dizzy and disorientated. Slept badly and muscles very fatigued thismorning. In spite of this I am going to try a much lower dose and see how I respond, hopeful I can gradually work up to the recommended dose.
I'm about to start working with a NP who is on the cutting edge of peptide usage. As a preview he says the immune system has to be modulated, followed by mitochondria and then hormone subsystems.
I have an appointment on the 19th.
Yes, he is one of the ME/CFS Clinician's Coalition doctors. Before helping ME/CFS patients, he was an AIDS doctor for over 25 years and knows about dysfunctional immune systems. Yes, he knows how to get them safely.Do you mind me asking about your doctor? Is he/she knowledgeable enough to treat ME/CFS? and, what about reliable sources of peptides, does he/she know about where to get them safely?
Yes, he is one of the ME/CFS Clinician's Coalition doctors. Before helping ME/CFS patients, he was an AIDS doctor for over 25 years and knows about dysfunctional immune systems. Yes, he knows how to get them safely.
Do you mean immediate like 30 minutes after taking it? Or immediate like a couple days of being on it?thanks for reply. happy for you.
was it immediate?
for me, as soon as I upped my dose to 150mcg I was totally crashed next day.
do you take in morning? evening?
do you take in morning or eve? I read on redit it causes insomnia in some so am wondering if I should switch to morning and IM so it's out of system by eveDo you mean immediate like 30 minutes after taking it? Or immediate like a couple days of being on it?
It was fairly immediate for me, within the first day I felt something was different but by the next dose, I was positive it was working great. It felt like all my neuroinflammation disappeared - I was no longer irritable, short tempered, impatient, heavily brain fogged, etc. I was in a better mood, my personality returned, felt better overall.
When I started it, I started 3 peptides at once: Thymosin Alpha-1, Thymosin Beta-4, & BPC157 (I stopped it after a couple months). I didn't slowly build up the dose. I started with 450mcg for TA1 & 675mcg for TB4, but I'm not someone who's very sensitive to meds. The first couple weeks, I took it in the mornings, but then did evenings like 8PM because I would forget usually doing the day and it was more convenient for me.
I had to take it everyday and if I missed a day, my malaise & irritability returned. After about a year, I could miss one day and be okay. Then two days. At 2 years, I could skip weekends (to save money) and even had some interruptions where I went 5-7 days without it and no symptoms returned. But after 2.5+ years, I stopped doing it because I was so sick and tired of the shots (with other meds I was at 4 shots/day) and I felt better. But now, I realize I need to restart it, as I've slowly gotten worse but in a different way, though I don't think its related to stopping TA1, as the benefits lasted >1 year.
Since you crashed from taking 150mcg, it may or may not be helpful for you. I would lower to a dose which doesn't cause PEM & stick with it for a couple months as you may need to build up or slowly shift/modulate your immune system. Since it had such a big effect for me, I expected other CFS patients would try it and help. But unfortunately, most other CFS patients don't respond well to it, or it has non effect.
man this sucks!I Crashed really hard on wednesday (Last weeks) after taking ta-1 0.5mg on monday and tb500 1mg on Tuesday.
Like really Bad atm Back to bed all day, increased Heartrate, Feeling Heart is exploding the whole Programm and it hasent gotten better since.
Also: i Just got my First Common Cold in 2 years, i havent Had one since getting sick! Unsure If its a good Thing since colds tend to mean you have a normal immune system If your donf get em too frequently.
I will Not Take it again too soon probably this is such a Nightmare atm
5 days on at 100mcg 2 days off then repeatSo you Take 2x 100mcg weekly or only 100mcg once a week?
This is interesting! I might retry It with way lower dosages when I am recovered from this severe Crash.
Just ranting, no information from this Point:
Man i Just hate this ducking duck disease of a duck. I can barely Go to the Kirchen ATM and i was housebound before meaning I could actually Play Computer for 3 hours a day without crashing (Crashed after more than 4 though) wich was so great for me i was so thankful for being able to do that since i think some have it worse and i am grateful for everything of course but man i cant even EAT at the Moment without having to lay down and get rhr of 110 this disease is such a Shitfest!!!