It's normal for us as CFS patients for every time we start a new supplement like me starting atp fuel to first have a worsening of symptoms right? I know it has some prebiotic and probiotic stuff in it along with other things... Seems like my nervous system gets intensified. Nerve pulsing and vibrating in chest and hands are more prominent and skin itching is more... Even how my arms shake me awake in the mornings... Do you start stuff and go down a tad and eventually get better from it? I heard that's what happens with ampligen too. Feel free to post your experience of starting supplements and your reactions.