I'm in treatment for autonomic dysfunction (primarily POTS) at Mayo Clinic, but I tested xmrv negative for both culture and PCR through VIP dx. I'm quite surprised, relieved, though apprehensive about false negatives.
My onset was gradual (extreme fatigue, during a time of intense personal and professional stress). The POTS and autonomic dysfunction, including inability to sleep, feeling profoundly brain-fogged, getting wired like crazy when in only slightly stressful situations, and neurasthemia in feet all started a couple weeks after I herniated a disk in my back. That seems to have been the triggering event for me, though about a year into things my EBV early antigen titers were elevated indicating a reactivated infection within the past year.
EBV tends to reactivate under stress, so my theory is that it was a consequence, not the cause.
Mayo's theory on autonomic dysfunction is that it can be triggered by any number of events. They routinely check for AChR antibodies, and treat with Mestinon on the basis of that theory, which I know has been quite helpful for many of their patients, at least in relieving POTS symptoms.
Incidentally, VIPdx, to my surprise, got my test results back in a week. I sent them in early December and got them back a week later. Given all the tales of the process taking weeks for so many others, I'm not sure what to think (perhaps my sample was just obviously negative - but who can say -- that's reading too much into things.)