Very very interesting. I wonder if they can catalogue unknown species or only those in their database.
I think only those in the database. But their database is huge. And variants will also be recognized without any database reference of the respective variant itself. Maybe if there was a high load of unrecognized DNA/RNA fragments, this would stick out. But traces will be indistinguishable from bias. There are other methods for the recognition of new pathogens, but you will need sufficient amounts of DNA/RNA regardless. CD Genomics is a world-wide provider with a broader and less specialized spectrum of genomic testing services.