supplements for energy

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Testosterone, Ginko ("mental energy"), L-Lysin + Valtrex, ß-Alanin, CreatineOrotate/Malate, LDX/C, COP and MSP front loading. (since my Vitamin-D levels are up, I mostly dont take anymore MSP)

I also eat several times a day and "float" my body with "fuel".
To make things easier for my gut I drink 2-3x daily shakes with fine grinded oats, nuts, brown rice powder, BCAAS/proteine, waizy maize, omega 3/6 oil and such things. The shakes contain nearly all necessary nutritions, it is cheaper then D-Ribose and gives me more energy.
I mostly use lower glyx foods that release over several hours the energy from the carbs. (high glycaemic index stuff like Vitargo, Malto seems not to work for me that good)
 
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You should consult a doctor to do some blood work if you are considering any immunomodulators like Inosine (or Immunovir Pranonbex which is pharma-grade stuff) and hormone like Testosterone.
Only if T-Levels are low (called "hypogonadism") a doctor will prescribe Testosterone. A TRT is in most cases a "life-time" decision (it will shoot down yours natural T-hormone production)

It is not wise to inject testosterone without consulting any doctor before.
(if yours dosing regime is bad, you will for sure get & drive "Roller-coaster")
 

raghav

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Try all the adaptogens one at a time. I find Rhodiola Rosea and Cordyceps sinensis help me a lot in terms of both physical and mental energy. If you are not the low cortisol type try Ashwagandha, 250 mg in the morning.
 

pattismith

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Patti could you tell me more about these treatments as in how they are purchased brand names how you take them and the amounts you take. Thank you.
I agree with @Hd-x that supplementing with testosterone is not an easy decision, specially for a woman, but it has shown to be efficient to help fibromyalgia women, and I can confirm it works for me. You can find the study and dosage on the net. (personally I use a lower dosage, because of some side effects= gingivitis at the proposed dose).

Ambroxol on the other hand can be bought without any prescription (although not in all the countries, so you can do a search on the forum, members give some way to find it). It's a mucolytic drug (totally benign), with analgesic properties, (like Lidocaine) and anti-inflammatory properties (on lungs and root ganglia).
Its used was discussed in fibromyalgia. A pill is 30 mg, you can try 1/2 to 3 pills per day and experiment with it.
The side effect I got at the begining was sleepiness.

Inosine is not a simple immunomodulator and adenosine receptor activator, it feeds the cells with hypoxanthine to the purines salvage pathway.
Checking your blood uric acid level before and during the treatment is a good security.
The side effects i got at first were headache, and loss of efficacity if taken every days.
The first time I took it without caffeine, it made me too sleepy.
Dosage used by ME/CFS specialists can vary depending on uric acid levels.

It's only when I took all these drugs together that I was able to tolerate them.

Cannot give my dosage, as I am still experimenting with it
 
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pogoman

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Mito cocktail for energy, ingredients vary depending on ones mito damage.

http://www.mitoaction.org/blog/mito-cocktail

For antioxidants, I've found Astaxanthin helps a lot. Just adding that has helped repair my sun damaged skin the past few months.
Also take vit C and olive leaf.

Regarding Ambroxol. The studies showing it helps for neuro issues because its a sodium channel blocker.
The prescription med oxcarbazepine is also a sodium channel blocker and may be a better choice for some as its fairly nondrowsy.
I've been on ox for a year, helps neuro pain very much with no side effects.
 

pattismith

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Regarding Ambroxol. The studies showing it helps for neuro issues because its a sodium channel blocker.
The prescription med oxcarbazepine is also a sodium channel blocker and may be a better choice for some as its fairly nondrowsy.
I've been on ox for a year, helps neuro pain very much with no side effects.
I know nothing about Oxcarbazepine, but reading the side effects of this anti-epileptic drug frightens me!

Ambroxol is a very soft drug (it is very different from Oxcarbazepine, and has no effect on epilepsy) , with new interest from the scientifict community for Parkinson and Gaucher diseases.

The fact I had problems tolerating it at the start doesn't mean others will experience the same sleepiness. It's worth a try.
 

pogoman

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I know nothing about Oxcarbazepine, but reading the side effects of this anti-epileptic drug frightens me!

Ambroxol is a very soft drug (it is very different from Oxcarbazepine, and has no effect on epilepsy) , with new interest from the scientifict community for Parkinson and Gaucher diseases.

The fact I had problems tolerating it at the start doesn't mean others will experience the same sleepiness. It's worth a try.
Its used off label for neuropathic pain, I am not epileptic by any means lol.
I've had no side effects altho its earlier parent med carbamazepine started giving me side effects after starting rituximab.

For what its worth I tried a bottle of ambroxol and it did nothing, researching I found both are sodium channel blockers altho I think they work on different channels.

Oxcarazepine definitely helped me, as you mentioned everyone is different and its worth a try.
 

btdt

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I don't have a doctor who treats ME MCS or Fibro.... I have a family doctor just now that is about it seems to me she does not have much interest from what I can gather. Had "treatment" in the past mostly antidepressants seizure drugs ... carbazepine was a very bad drug reaction for me. Still mucking around doing trial and error by myself mostly supplements... ect. Always looking around for what may help.
Ambroxol on the other hand can be bought without any prescription (although not in all the countries, so you can do a search on the forum, members give some way to find it). It's a mucolytic drug (totally benign), with analgesic properties, (like Lidocaine) and anti-inflammatory properties (on lungs and root ganglia).
Its used was discussed in fibromyalgia. A pill is 30 mg, you can try 1/2 to 3 pills per day and experiment with it.
I tend to have a reactions to things other people don't generally react to.... had a reaction to lidocaine for instance... so when you mention this drug is like lidocaine... I have to ask in what way? In that it is common and generally non reactive for most?

My reaction to lidocaine was investigated about 18 months after the fact I was given a small dose under the skin with no reaction... it was suggested to me that I had a TIA at the same time the dentist injected the lidocaine...the reaction or if it was one was systemic after affects lasted months. I did not see a dentist for a long time after that out of fear. I have had procaine I think it is called since and been ok.

there is this
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189001/
Conclusions
Our data suggest that raising serum UA levels by the oral administration of inosine treatment may benefit patients with MS. Improvements in EDSS and a reduction in lesion activity were noted. Studies in a larger cohort are indicated and will help to elucidate the mechanistic effects of the treatment.

makes inosine interesting... to me
I know I am still all over the map thanks for the help
 

pattismith

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@btdt
I was mostly intolerant to most drugs and most supplements (headache with most, brain fog, dizziness, weakness, stiffness, etc), but can't remember if I had any experience with lidocaine in the past.
Ambroxol is a sodium channel blocker like lidocaine, but I couldn't say if a reaction to Lido makes it more likely to happen with ambroxol.
the fact ambroxol is given by mouth may be safer, you may do a search and see the known side effects, but it is one of the safest drug I have tried since I experiment.
I got sleepy and weak with Ambroxol, but now that I take Testosterone, I don't have any longer any difficulty to tolerate it, even with higher doses.
I can also tolerate Inosine now too.
Inosine can raise you uric acid blood level, so you have to pay attention to that, because too much can generate uric acid stones/cristals in kidneys and articulations. Your doc can check your blood levels, it 's cheap test.
 
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btdt

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Vijayendran Chandran and Daniel H. Geschwind of UCLA and their colleagues identified the components of the network by finding groups of genes with expression levels that increased or decreased together over time after various injuries to peripheral nerves in rodents. Next, they analyzed a publicly available database of gene expression patterns triggered by about 1,300 biologically active small molecules. They looked for the compound with a pattern that best matched the one observed in their gene network. The result was ambroxol, a drug that helps clear mucus in the lungs. When given to mice with optic nerve lesions, the compound induced a modest level of neuron regrowth.
https://cen.acs.org/articles/94/i9/Looking-gene-networks-trigger-nerve.html