Sublingual vs oral Glutathione ...

[PeterPositive]

Hello,
I am currently taking between 1000 and 1500mg of oral reduced glutathione, which is helping a bit.

I've noticed that there are a couple of brands that provide sublingual versions, which in theory should be easier to absorb.
http://www.detoxpeople.eu/index.php?l=product_detail&p=517
http://www.supersmart.com/en--Antioxidants--Perlingual-glutathion-100-mg--0402

Are you familiar with any of these products? Would you recommend switching from regular capsules to sublingual?

Also I've noticed that the dosages are quite different. One capsule delivers 500mg while these tablets provide 50-100mg. Any comments.

Thanks in advance

 

[PeterPositive]

While at it I have found a third option which is Acetyl-Glutathione:
http://www.nleducation.co.uk/resources/reviews/oral-glutathione-equivalent-to-iv-therapy/

which seems to be effective as an oral supplement. Interesting. Anyone is using this?

 

[Thinktank]

Maybe transdermal GSH is even a better option? It's better absorbed than oral and sublingual GSH.

 

[PeterPositive]

Maybe transdermal GSH is even a better option? It's better absorbed than oral and sublingual GSH.

Could be. According to this study it doesn't look like there is a major difference and apparently the main issue is getting glutathione inside cells.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628138/

thanks

 

[PeterPositive]

So if I understand this correctly it appears that it's not very difficult to raise glutathione levels in the blood, but it's difficult to make it go inside the cell.

If that's correct I don't understand exactly why the IV route should be more effective than oral or sublingual. At the end of the day all routes will just add more glutathione in the blood stream. It's not clear to me why IV have a better chance to deliver it to the cells?

Is it a matter of dosage? The more you put in the blood stream the more chances that a small % goes inside the cells?

Also reading the positive comments about oral glutathione on iHerb and such, seems to indicate that it's actually efficacious. Unless it's all placebo... which would seem kind of strange.