bensmith
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This study was presented in the main news of Tunisia
(Translated from french)
Finally, post-Covid endothelial dysfunction is a reality which partly explains the symptoms of post-covid " TUN-EndCOV, the first large Tunisian multicenter study of endothelial function in 613 post-COVID patients has made the history of long-COVID less mysterious. Preliminary results were that 285 patients (47.6%) had endothelial dysfunction and that it was severe in 134 (22%) patients. Endothelial dysfunction was associated with an age ≥ 45 years, various cardiovascular risk factors, the clinical and CT scan severity of COVID and an infra-clinical myocardial lesion objectified by the overall longitudinal strain. Patients with symptoms of long COVID had more endothelial dysfunction. And most notably, chest pain. So, is there any treatment that could improve this severe endothelial dysfunction and therefore the symptoms? Among our patients with severe endothelial dysfunction, sulodexide was associated with a significant improvement in endothelial function compared to the spontaneous evolution group. The 3-month and 12-month follow-up will provide us with answers on the prognosis of this post-covid endothelial dysfunction. We would like to thank all the teams and investigators for their collaboration and who made this dream a reality. The Sfax cardiology team (Dr Selma Charfeddine, Slim Torjmen, Raouya Trabelsi, Imen Gtif, Pr Rania Hammami, Dr Amine Bahloul, Pr Samir Kammoun, from Mahdia (Dr Ibnhadjamor Hassen and Salma Kraiem and of pneumology Dr Imen Touil), Pr Salem Abdessalem, Pr Faouzi Addad, dr Kais Ben Salem The internal medicine team of Marsa (pr Kamel Bouslama, dr Zeineb Meddeb) and the team of cardiology and pulmonology of medenine (Prof. Sami Milouchi and Prof. Jamel El Ghoul) To follow the webinar where the results of this first study carried out on a global scale and carried out by a machine
As you have seen they suggest sulodexide as a treatement ...
A youtube video where doctors explain more the study(it's in french but there are english subs) :
in the video they said that the endothelial cells have ACE2 receptors which the virus will attach to and detroy the cell.
If you google endothelial dysfunction symptoms this is what it returns :
Chest pain, squeezing or discomfort (angina), which may worsen during daily activities and times of stress
Discomfort in your left arm, jaw, neck, back or abdomen associated with chest pain
Shortness of breath
Tiredness and lack of energy
I'll post the research paper once it's published
-not my words, a redditor.
(Translated from french)
Finally, post-Covid endothelial dysfunction is a reality which partly explains the symptoms of post-covid " TUN-EndCOV, the first large Tunisian multicenter study of endothelial function in 613 post-COVID patients has made the history of long-COVID less mysterious. Preliminary results were that 285 patients (47.6%) had endothelial dysfunction and that it was severe in 134 (22%) patients. Endothelial dysfunction was associated with an age ≥ 45 years, various cardiovascular risk factors, the clinical and CT scan severity of COVID and an infra-clinical myocardial lesion objectified by the overall longitudinal strain. Patients with symptoms of long COVID had more endothelial dysfunction. And most notably, chest pain. So, is there any treatment that could improve this severe endothelial dysfunction and therefore the symptoms? Among our patients with severe endothelial dysfunction, sulodexide was associated with a significant improvement in endothelial function compared to the spontaneous evolution group. The 3-month and 12-month follow-up will provide us with answers on the prognosis of this post-covid endothelial dysfunction. We would like to thank all the teams and investigators for their collaboration and who made this dream a reality. The Sfax cardiology team (Dr Selma Charfeddine, Slim Torjmen, Raouya Trabelsi, Imen Gtif, Pr Rania Hammami, Dr Amine Bahloul, Pr Samir Kammoun, from Mahdia (Dr Ibnhadjamor Hassen and Salma Kraiem and of pneumology Dr Imen Touil), Pr Salem Abdessalem, Pr Faouzi Addad, dr Kais Ben Salem The internal medicine team of Marsa (pr Kamel Bouslama, dr Zeineb Meddeb) and the team of cardiology and pulmonology of medenine (Prof. Sami Milouchi and Prof. Jamel El Ghoul) To follow the webinar where the results of this first study carried out on a global scale and carried out by a machine
As you have seen they suggest sulodexide as a treatement ...
A youtube video where doctors explain more the study(it's in french but there are english subs) :
in the video they said that the endothelial cells have ACE2 receptors which the virus will attach to and detroy the cell.
If you google endothelial dysfunction symptoms this is what it returns :
Chest pain, squeezing or discomfort (angina), which may worsen during daily activities and times of stress
Discomfort in your left arm, jaw, neck, back or abdomen associated with chest pain
Shortness of breath
Tiredness and lack of energy
I'll post the research paper once it's published
-not my words, a redditor.