I'm wondering whether this is consistent with MCAS, which is that on some nights I wake up a few hours after going to sleep and there's a lot of urine, whereas other nights I can go 12+ hours at night and wake up only feeling a slight need to urinate. I'm wonder if this is could be due to the chemicals released by mast cells (my diet is quite uniform and I have essentiallly controlled for dietary factors). I have been taking 20 to 30 mg of loratidine over the last week or so, and this odd pattern has continued. I'm in my mid 50s and don't have diabetes, heart disease/atherosclerosis, or other typical chronic issues (just things associated with MCAS, including osteoporosis, denegerative disc disease, orthostatic hypotension, rashes that come and go quickly, dry eye that tear easily, difficulty swallowing, heat intolerance, sleep disturbances, runny nose while eating and in the cold, chronic post nasal drip, weakness/fatigue, grogginess/"heavy" head, etc.). I am going to try and find a local MCAS specialist, but I haven't been out much due to covid concerns.