Start-up EBViously founded

[SWAlexander]

German Center for Infection Research:
EBViously, a spin-off of Helmholtz Munich, officially started operations on 11 November 2024. The company is developing a preventive vaccine against diseases caused by the Epstein-Barr virus (EBV). The aim is to protect people from a range of serious diseases such as infectious mononucleosis, secondary diseases such as multiple sclerosis and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and certain types of cancer.


EBViously is based on a research project supported by Helmholtz Munich and the German Center for Infection Research (DZIF). The vaccine was developed by leading scientists in the field of Epstein-Barr virus research and the aim is now for the company to carry out professional product development.
Continue reading: https://www.eurekalert.org/news-releases/1068503

 

[Norwegianlad]

If they manage to prevent people getting ME/CFS, or to a certain degree, with vaccines like this, wouldn't it slow down the search for a cure for the people that already have it?

 

[heapsreal]

If they manage to prevent people getting ME/CFS, or to a certain degree, with vaccines like this, wouldn't it slow down the search for a cure for the people that already have it?

Good question. I think it may have for polio/post polio syndrome.

 

[SWAlexander]

cure for the people that already have it?

This is the question I asked on BlueSky: https://bsky.app/profile/swalexander.bsky.social/post/3ldm2pcvxk224

I can't help but wonder how psychologists or even psychiatrists, who claim that ME/CFS is purely psychological, would respond to reading about this groundbreaking discovery.

 

[cfs since 1998]

If they manage to prevent people getting ME/CFS, or to a certain degree, with vaccines like this, wouldn't it slow down the search for a cure for the people that already have it?

If they can prove an EBV vaccine prevents ME/CFS then it would prove EBV is a cause, or the cause, of ME/CFS and this would help focus research on treatments.

 

[Gijs]

Vaccination has a downside. Because people also get ME/CFS after a vaccination. Post vaccination fatigue syndrome. Just look at long covid after vaccination. There are several viruses and infections that can lead to ME/CFS. Only if EBV is THE main cause then this vaccine could help. But it takes at least 30 years to prove that. HHV6 and 7 are also seen as potential causes. Prusty et al.

 

[Norwegianlad]

Vaccination has a downside. Because people also get ME/CFS after a vaccination. Post vaccination fatigue syndrome. Just look at long covid after vaccination. There are several viruses and infections that can lead to ME/CFS. Only if EBV is THE main cause then this vaccine could help. But it takes at least 30 years to prove that. HHV6 and 7 are also seen as potential causes. Prusty et al.

Why at least 30 years?

 

[Wishful]

If someone has the predisposition to develop ME, it might reduce the number of victims who trigger on EBV, but maybe they'll trigger on some other virus, vaccine, or some other factor. Remember, most people have been infected with EBV, but not everyone with EBV develops ME.

Question: have any PWME been found who don't have the EBV antibodies? If yes, that might be evidence that ME is not due to EBV.

 

[heapsreal]

If someone has the predisposition to develop ME, it might reduce the number of victims who trigger on EBV, but maybe they'll trigger on some other virus, vaccine, or some other factor. Remember, most people have been infected with EBV, but not everyone with EBV develops ME.

Question: have any PWME been found who don't have the EBV antibodies? If yes, that might be evidence that ME is not due to EBV.

Apparently they don't find anyone with MS that doesn't have ebv antibodies.

In my case and I've heard it happen to others with cfs, ebv was or apart of the triggering infection in cfs. I tested igg positive to ebv, life long antibodies supposedly, probably tested about 4 weeks after intial infection, so maybe too late for iga testing. Earlier in the year also had mono symptoms from cmv and also was tested for ebv then which was totally negative. Several years later tested totally negative to ebv atleast twice.

Something similar was seen in the Lake Tahoe i believe.

 

[Gijs]

Why at least 30 years?

To understand whether EBV vaccines can also combat MS or ME/CFS, a large portion of the population would need to be vaccinated and then followed for decades.