hmm it's totally worn off by now and I took it around 5, but this had t4, supposed 2 b more long-lasting
SPINA THYR a research tool to evaluate thyroid function, deiodinases activity, TH resistance
- Thread starter pattismith
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I keep trying to remember to take lithium but i don't know where it is in my house I need to set some kind of reminder 
Anyway, despite the elegance of your theory, I hope you're wrong that CFS patients need the super low dose approach, because I want my more exoteric approach to work and not have to fret more, haha.
Anyway, despite the elegance of your theory, I hope you're wrong that CFS patients need the super low dose approach, because I want my more exoteric approach to work and not have to fret more, haha.
I know what you mean but I think you want to avoid these hypomanias. They feel good but they will cause your receptors downregulate and that will lead to depression, trust me on that one. Lithium orotate, even a very small dose, dampens this effect.
Depression that follows hypomania is the worst.
Last night I slept for over 14 hours! jesus christ. I wonder if this is an effect of the thyroid. I almsot never sleep this long. It didn't feel like refreshing sleep but a kind of awful, overwhelming torpor
Heart rate 125 bpm while sitting up, being out of breath... about 1 hour after taking cynoplus
hmm my bp is overly high but I feel pretty good from tonight's thyroid dose
it's 150/98
and then 129/83 the last time (five minutes later)
Okay so the odd thing is
i took an amount that made me feel all right and then a tiny bit on the manic side (but not much) and then took the bp and it was high
and then I kept sitting down and it went down to like 120/80 over five minutes but now I feel absolutely dead-tired, not good
it's like the t3 spikes too much
I haven't been very organized about keeping track of symptoms unfortunately but I do think the thyroid has been helping, or at least I feel good about thyroid being involved in my recovery. Unfortunately I'm not sure if @Iritu1021 is right and I need a lower dose. Going to keep trying the medium doses for a little while but track blood pressure more.
I don't get that scared about a one time reading like that but things have been so tough that I rarely remember to take vitals, besides pulse and temp, and I'm confused about it helping with symptoms but raising bp.
it's 150/98
and then 129/83 the last time (five minutes later)
Okay so the odd thing is
i took an amount that made me feel all right and then a tiny bit on the manic side (but not much) and then took the bp and it was high
and then I kept sitting down and it went down to like 120/80 over five minutes but now I feel absolutely dead-tired, not good
it's like the t3 spikes too much
I haven't been very organized about keeping track of symptoms unfortunately but I do think the thyroid has been helping, or at least I feel good about thyroid being involved in my recovery. Unfortunately I'm not sure if @Iritu1021 is right and I need a lower dose. Going to keep trying the medium doses for a little while but track blood pressure more.
I don't get that scared about a one time reading like that but things have been so tough that I rarely remember to take vitals, besides pulse and temp, and I'm confused about it helping with symptoms but raising bp.
Well i've only been taking cynoplus once a day and I would say the increased energy only lasts about 6 hours (i'ts probably the t3 in the cynoplus, not the t4)
Idk. I don't ever use the energy scale. Without it I normally feel miserable and get muscle pain and incredible brain fog just even while sitting down, without exerting myself. It gets rid of that and I feel I have a little extra energy and POTS seems to get better while on it , although a couple times it made it a little worse when first kicking in (I should take more detailed notes).
It's hard to tell if it's too much or too little because of the blood pressure thing and also that it's led to me sleeping a little less, which used to happen when i took stimulants for ADHD (not that it keeps me up, to be clear, but that I don't sleep for as long once I go to sleep, which seems like a problem)
But the positives seem like that I feel, well, just decent, and can think and talk without getting worn out, and even walk around some , when on it
Idk. I don't ever use the energy scale. Without it I normally feel miserable and get muscle pain and incredible brain fog just even while sitting down, without exerting myself. It gets rid of that and I feel I have a little extra energy and POTS seems to get better while on it , although a couple times it made it a little worse when first kicking in (I should take more detailed notes).
It's hard to tell if it's too much or too little because of the blood pressure thing and also that it's led to me sleeping a little less, which used to happen when i took stimulants for ADHD (not that it keeps me up, to be clear, but that I don't sleep for as long once I go to sleep, which seems like a problem)
But the positives seem like that I feel, well, just decent, and can think and talk without getting worn out, and even walk around some , when on it
I don't think my experience has been as extreme as @Iritu1021 's described experience with the POTS symptoms increasing, etc., but it's also not totally perfect, so I'm not sure what to do
The tricky part is still distinguishing between good and "bad" energy.
Last night while falling asleep I felt sorta on the feverish side like possibly a little hyperthyroid, and when I woke up I felt sorta similar but my pulse and temp were actually on the low side (I don't think pulse and temp are perfect indicators but still)
I used to take ritalin for ADHD. Methylphenidate is different pharmacologically than amphetamine and I think can be beneficial in small doses. When I took my 10 mg dose , as long as I had it without coffee or additional stimulants, I actually felt more relaxed but also energized at the same time
After I got Lyme, one of the first things that was odd was my reaction to methylphenidate was far worse. Didn't happen overnight but I couldn't tolerate it. Either it would barely cut through the brain fog, or it would cause all the bad symptoms with none of the good--i would be shaking and feel extreme adrenergic symptoms and not be able to sleep for the whole night after, but not really ever focused.
Anyway I wonder why that is, but the paradoxical relaxation while being stimulated and focused is I think the ideal state physiologically and hopefully I can get there with the thyroid. High(ish) bp not a good sign but I have to take more consistentally
Last night while falling asleep I felt sorta on the feverish side like possibly a little hyperthyroid, and when I woke up I felt sorta similar but my pulse and temp were actually on the low side (I don't think pulse and temp are perfect indicators but still)
I used to take ritalin for ADHD. Methylphenidate is different pharmacologically than amphetamine and I think can be beneficial in small doses. When I took my 10 mg dose , as long as I had it without coffee or additional stimulants, I actually felt more relaxed but also energized at the same time
After I got Lyme, one of the first things that was odd was my reaction to methylphenidate was far worse. Didn't happen overnight but I couldn't tolerate it. Either it would barely cut through the brain fog, or it would cause all the bad symptoms with none of the good--i would be shaking and feel extreme adrenergic symptoms and not be able to sleep for the whole night after, but not really ever focused.
Anyway I wonder why that is, but the paradoxical relaxation while being stimulated and focused is I think the ideal state physiologically and hopefully I can get there with the thyroid. High(ish) bp not a good sign but I have to take more consistentally
I take small crumbles of a cynoplus 120/30 mcg tablet, in the evening once a day so far. I kind of do it by feel now. Started with one eighth of a tablet.
Doing based on this https://www.patreon.com/posts/demystifying-14839477
Doing based on this https://www.patreon.com/posts/demystifying-14839477
The "high energy but relaxed" state with high metabolic energy but not stress hormones, is what i'm going for. LDN helped me get around and do stuff but I think it increased stress hormones and bp a lot-- it increases ACTH even at low doses I think
I am not taking it.
Ray Peat has very interesting theories and I think what he says about diet is sound, but I definitely view everything with a grain of salt until it works.
But yes, his and Szent-gyorgyi's ideas are based on this idea of "energy and structure are interdependent" which I think seems sound... Naviaux would probably agree, modern medicine and lots of research has neglected bioenergetics for too long. Metabolism probably underpins every single disease in some way. I'm not sure that Ray's right about everything, but these broader ideas are probably correct.
Haidut on the Ray peat forum does a pretty good job of combing through research very thoroughly and thus presenting things in a way where he doesn't just say "ray said x", he presents convincing cases, and I think he differs from ray on some things
Ray Peat has very interesting theories and I think what he says about diet is sound, but I definitely view everything with a grain of salt until it works.
But yes, his and Szent-gyorgyi's ideas are based on this idea of "energy and structure are interdependent" which I think seems sound... Naviaux would probably agree, modern medicine and lots of research has neglected bioenergetics for too long. Metabolism probably underpins every single disease in some way. I'm not sure that Ray's right about everything, but these broader ideas are probably correct.
Haidut on the Ray peat forum does a pretty good job of combing through research very thoroughly and thus presenting things in a way where he doesn't just say "ray said x", he presents convincing cases, and I think he differs from ray on some things
So a few of the times I took cynoplus I slept for only 7 and 1/2 hours and couldn't get back to sleep the next morning, which is disturbing. But then another time I took cynoplus and I slept for 14 hours!!!! It's very odd.