Could well be any of those environmental sensitivities. An air filter made a big difference for me. But I'll caution that the effect I have with clothes (and also the sofa or bedding I'm sitting on) is not as simple as feeling the effect at the point of contact. Right now my face is itching, and from experience I'm fairly sure that's a result of having the keyboard on my lap, some dust on the sofa, and/or the clothes I'm wearing. All of those things increase my sensitivity in general, and they are the underlying cause of the itching on other parts of my body. And anti-histimines have no effect at all for me, because this sensitivity is not a regular allergic response.It's the parts of bare skin, not touching clothes, that bother me. I feel like if I could cover all my skin it would help a little, but that is too inconvenient to cover neck and wear long sleeves and gloves. And my face would still be exposed. It's not itchy, just sensitive. I hope it's not diet related. I already eliminated most foods from my diet. I wonder if it is influenced by household mold and toxins, pollen allergies, or cleaning chemicals.
Zyrtec was the one I was on before as well. They've got me on Atarax at the moment. It's hard to tell, but I think it helps a little more, and I seem to sleep a little better on it as well. It's one of the older anti-histamines.
Did you look up dermographism, by the way? Apparently with that, some people end up on two types of antihistamines at once. I'm booked to see the dermatologist soon, so I'll ask about that. Not everyone does well on antihistamines, though, some people prefer other options.
My sensitivity seems increased because of recent supplements I added. I started B Complex with metafolin, methyl B12, and some others before that.
Have you tried cutting back on your supplements to see if it calms down.
Does anyone know the best way to raise this without making the specialist think you're one of those annoying patients who wants to diagnose themselves?