Hip
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The thing that's weird about it all is that it is markedly worse the more fatigued I am. It doesn't preempt the fatigue - I start feeling tired and then these symptoms get worse.
The virus I caught (detailed on my website here), which is likely a Coxsackie B virus, not only triggered my ME/CFS but also triggered chronic nasal and sinus congestion and post-nasal drip in a large number of people who caught the same virus. When I say chronic nasal and sinus congestion, I am mean chronic: I am talking about a condition that persists indefinitely for years.
I think coxsackievirus B may be behind many cases of chronic nasal congestion or sinusitis with no apparent cause (ie, when there is no bacterial or fungal infection found).
One of the symptoms this virus induced in me was severe generalized anxiety disorder. I noticed that on days when my anxiety levels were more severe, my nasal and sinus congestion / inflammation was worse.
It's always hard to determine whether there is a causal relationship between two such associated symptoms, but in this case, I found that any treatments that helped clear my nasal and sinus cavities of congestion / inflammation would also immediately reduce my anxiety levels by a noticeable amount.
For example, if I used a face steamer to help clear my nasal and sinus congestion, within 10 ot 20 minutes this would also reduce anxiety.
Other supplements and drugs that I used to reduce this congestion / inflammation also noticeably reduced my anxiety levels. So that suggests that this nasal and sinus congestion / inflammation does play a causal role in creating anxiety symptoms.
If you are interested, I posted a list of supplements that I found clear my nasal and sinus congestion / inflammation in this post.
In particular, I found the supplement N-acetyl-glucosamine (NAG) orally, at a dose of around 700 to 1400 mg daily, clears the sinuses well if you take it daily on an empty stomach.
Are you aware of the vagus nerve infection hypothesis of ME/CFS? This posits that infection / inflammation in or around the vagus nerve can cause ME/CFS symptoms by what's known as the sickness behavior response.
Well, the trigeminal nerve in the nasal and sinuses cavities also can trigger the sickness behavior response in the brain when this nerve detects inflammation, so this may be how inflammation in the nose and sinuses can cause fatigue
For treatment of sinus infection, the best thing I've found are ozone injections. My doctor injects ozone into my gums above my canines, and it works great.
I used a transdermal ozone application technique, applied to the whole body (detailed here), which you can do yourself easily at home, I and found that this has a significant nasal/sinus cavity clearing effect. My nose and sinuses would be much clearer after ozone.
My doctor now has me on a 100% dairy free diet to see if possibly I have a food intolerance that is causing at least some of my sinus issues as I also have allergies that four allergy tests later all come back negative.
I few years ago when I was suffering from severe anxiety, and as explained above I noticed a connection between my sinus and nasal congestion and my anxiety, so I decided to go dairy-free, and I found this helped both my congestion / inflammation and my anxiety.
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