Severe Migraine with even tiniest crumb of Metafolin or active B12...

[Lola23]

I posted this in 3 other threads but then thought it would work better to create my own thread.

Hi guys I am new to this website. I totally believe methylation is key to my healing from CFS/ fibro. Two years ago I took 800mcg folic acid and felt AMAZING for two weeks. I slept better. My back pain went away. The depression lifted. Then all of a sudden I started to get a migraine every time I took the folic acid. Even when I halved the dose and took it a month later, I still got a migraine. Now two years later, I still can't tolerate even a quarter of a tablet of metafolin. What is going on? I also get an immediate migraine from B12...even if I nibble off the slightest bit of a tiny active B12, I get a SPLITTING headache to the point of having to lie in bed in pain for the next 24 hours.

1. Does anyone know what could be going on? Or what I could do to be able to tolerate folic acid and B12? I know if I could tolerate these vitamins, I would feel much better. For some reason B6 or P5P gives me no problem at all.
2.What other vitamins and cofactors do I need to be taking to make sure these work well? Is this about potassium?
3. What kind of testing should I get done to see what deficiencies I have?

Thank you for all your help!

Lola

 

[Crux]

Hi Lola;

This is a very difficult problem... and I'm still working on this too. It would be a good idea to get some tests done, such as the ones that Rich recommends. (Someday, I will.)


From the reading I've been doing about B12 and Folate, one possibility for intolerance may be that there isn't enough zinc available to counter-balance their effects. So maybe a small amount of supplemented zinc would help.

Potassium has helped some of my milder headaches, but zinc has helped with my more migraine types. Magnesium is also effective.

 

[Lola23]

Hi Crux,

Yes I just want to figure out what kind of testing I need and what kind of doctor I should go see?

Lola