- Messages
- 14
Hello everyone,
I've been grappling with CFS/ME and long COVID since 2019, which has severely impacted my daily functioning due to persistent brain fog and fatigue. See my other post [here](https://forums.phoenixrising.me/threads/advice-i-am-seeing-a-psychiatrist-and-a-cardiologist-what-should-i-suggest-to-them-to-ease-my-brain-fog-and-fatigue.92519/).
Currently, I'm on a regimen that includes mirtazapine (7.5 mg) and trazodone (50 mg) which were prescribed since 2021 for sleeping purposes. Previously, I have also taken Lyrica from 2021 to 2023 and was on SSRIs for almost a decade until stopping them in 2021.
Lately, I've noticed that my mood has been increasingly affected, which might be worsening my cognitive symptoms. I've been reading about Rexulti (an Abilify variant) and fluvoxamine, and both seem promising in different aspects. I am considering adding one of them to my treatment plan but am unsure which might be more beneficial given my complex health history.
I would really appreciate insights from a pharmacology standpoint with these medications, in fact, I am already on Rexulti for 2 days and would say that mood has been slightly better, but brain fog maybe reduced by 20% (say from 7/10 to 6/10 severity in terms of sensory overload). I am just struggling to figure which should I experiment first since psy medicines are notoriously hard to taper off and I do not want to get the order wrong.
I've been grappling with CFS/ME and long COVID since 2019, which has severely impacted my daily functioning due to persistent brain fog and fatigue. See my other post [here](https://forums.phoenixrising.me/threads/advice-i-am-seeing-a-psychiatrist-and-a-cardiologist-what-should-i-suggest-to-them-to-ease-my-brain-fog-and-fatigue.92519/).
Currently, I'm on a regimen that includes mirtazapine (7.5 mg) and trazodone (50 mg) which were prescribed since 2021 for sleeping purposes. Previously, I have also taken Lyrica from 2021 to 2023 and was on SSRIs for almost a decade until stopping them in 2021.
Lately, I've noticed that my mood has been increasingly affected, which might be worsening my cognitive symptoms. I've been reading about Rexulti (an Abilify variant) and fluvoxamine, and both seem promising in different aspects. I am considering adding one of them to my treatment plan but am unsure which might be more beneficial given my complex health history.
I would really appreciate insights from a pharmacology standpoint with these medications, in fact, I am already on Rexulti for 2 days and would say that mood has been slightly better, but brain fog maybe reduced by 20% (say from 7/10 to 6/10 severity in terms of sensory overload). I am just struggling to figure which should I experiment first since psy medicines are notoriously hard to taper off and I do not want to get the order wrong.
