For the first several decades with CFS I had severely white palms - no colour. All of a sudden, while on very high antioxidant therapy, I developed Rudolph the Reindeer palms. It worried the hell out of me because it looked like a red pen had leaked and it had gone all over my palms. I actually looked for the pen and ink for a minute or so: no sign whatsoever. This stopped within hours, but ever since I have had normal palms, although sometimes they do go a little red - right now they are a healthy shade of all-over pink.