another link between CFS and insulin resistance?
I have run across some interesting information regarding insulin resistance and CFS. I don't know if this is accurate or relevant, but I do know that it worth looking into.
This has implications far beyond what you posted. Remember the study from de
Meirleir on very long term patients? They all had very high levels of
bacterial lipopolysacharide in their blood, which correlated with severity.
This implies, via a similar argument to the gum disease one, that ME and CFS
patients could develop insulin resistance from their immune response alone.
Protecting the gut would be the primary method to fix this, at least until
we understand more of the mechanisms.
(I have Paula's permission to repost this
----- Original Message -----
From: "Paula Carnes" <firstname.lastname@example.org>
To: "Paula Carnes" <email@example.com>
Sent: Friday, June 04, 2010 2:08 AM
Subject: [CPAR] Gum disease and inflammation
Dr. Mirkin writes a nice summary of the issues with gum disease. What he
doesn't cover is how to effectively treat it. I would be interested in
further ideas on this. Paula Carnes
Dear Dr. Mirkin: Do bleeding gums increase risk for diabetes as well as for
After reviewing 690 papers, doctors at the University of Edinburgh, UK,
report that treatment of gum disease in type 2 diabetes (not type 1) can
lower blood sugar levels and HBA1C, a test for cell damage (Cochrane
Database of Systematic Reviews, May 2010). Patients with gum infections are
at high risk for developing Type 2 diabetes (Journal of Public Health
Dentistry. December 2009).
Bleeding gums are usually caused by infections. Chewing drives bacterial
endotoxins from the gums into the bloodstream (Journal of Periodontolology,
January 2002). Your body responds to this invasion of bacteria with
inflammation: producing huge amounts of cells and proteins to kill the
germs, but they also block insulin receptors to raise blood sugar levels.
Adults who brush their teeth less than once a day have increased risk for
gum disease, a 70 percent increased risk for heart disease, and higher CRP
and fibrinogen blood tests signifying inflammation (British Medica Journal,
People with bleeding gums should seek treatment because they are at
increased risk for heart attacks, strokes and diabetes.
Sometimes treatment is just a short course of antibiotics, or you may need
extensive dental repair. For more information and journal references see
Las Vegas, NV
YES, certainly post the whole thing. Also add that one patient in the
Incline Village outbreak said the early cfs cases had onset of gum disease
as an early sign of illness. It looks like some infection found in cfs also
infects the gums????
I hope this opens up some new considerations in the CFS diabetes debate.