rebecca1995
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http://www.virology.ws/2010/01/27/x...m_campaign=Feed:+VirologyBlog+(virology+blog)
Dr. Racaniello's new entry is on a study from last year: "Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer". (http://jvi.asm.org/cgi/content/abstract/83/14/6995)
Racaniello writes,
Dr. Racaniello's new entry is on a study from last year: "Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer". (http://jvi.asm.org/cgi/content/abstract/83/14/6995)
Racaniello writes,
Xenotropic murine leukemia virus-related virus (XMRV) has been detected in prostate cancer tissues and is therefore a candidate tumor virus. XMRV, which has also been implicated in chronic fatigue syndrome, was first isolated from prostate tissue. Therefore it made perfect sense to determine whether SEVI, which originates from the prostate gland, enhances XMRV infection.
The observation that SEVI enhances XMRV infection is consistent with the possibility that the virus is sexually transmitted. Men with a history of prostatitis or sexually transmitted infections appear to have a higher risk of acquiring prostate cancer. However, the effect of a prostate-derived peptide on XMRV infection might be coincidental: the amyloid fibrils could stimulate infection by other viruses, as noted by the virologists who discovered SEVI...