Basilico
Florida
- Messages
- 948
Here's a potential problem, at least in my eyes: He cannot prove it's not an active infection at play in a significant portion of ME/CFS patients, regardless of whether it's IOM or CCC or ICC criteria, or much lesser diagnostic iterations.
Actually, Ron Davis did prove that CFS is not the result of an infection in the blood. He searched for viral DNA (which is much more precise and accurate than looking for antibodies as most CFS docs are currently doing) and he couldn't find anything significant - the healthy controls actually had slightly more evidence of viral infection than severe CFS patients.
While it is possible that there's an infection that can only be detected in the tissues (or maybe hiding in the vagal nerve), after listening to what he's learned so far, an infection seems unlikely. When he took cells from a severe CFS person and put them in the plasma of a healthy person, those cells behaved like a perfectly healthy cell. So he knows there's a problem with something in the plasma but not in the cells - I don't think this is consistent with a viral infection (which works by highjacking cells).
If you haven't already, you should check out what he said that the CFS symposium at Stanford in August. Here's a link that @Stukindawski posted on another thread with clickable links. So far, I've watched the Naviaux and Ron Davis parts, they are outstandingly informative.
Clickable links to each part of the stream:-
(Click the timestamps to go directly to that point in the video)
Introduction & Welcome: Linda Tannenbaum and Ashley Haugen (00:10)
Opening Remarks: Ron Davis: (00:14)
Morning speakers:
Robert Naviaux: The metabolism of the cell danger response, healing, and ME/CFS (00:18)
Chris Armstrong: ME, metabolism and I (00:38)
Jonas Bergquist: In search of biomarkers revealing pathophysiology in a Swedish ME/CFS patient cohort (00:53)
Maureen Hanson: Probing metabolism in ME/CFS (01:46)
Neil McGregor: Genome-wide analysis & metabolome changes in ME/CFS (02:05)
Alan Light: Gene variants, mitochondria & autoimmunity in ME/CFS (02:21)
Panel discussion: Morning speakers (02:42)
Afternoon speakers:
Baldomero Olivera: A novel source of drugs: the biodiversity of oceans (04:37)
Mario Capecchi: The role of microglia in neuropsychiatric disorders (04:57)
Mark Davis: Is CFS/ME an autoimmune disease? (05:14)
Alain Moreau: New research strategies for decoding ME/CFS to improve diagnosis and treatment (06:06)
Wenzhong Xiao: Big data analysis of patient studies of ME/CFS (06:25)
Ron Davis: Establishing new mechanistic and diagnostic paradigms for ME/CFS (06:44)
Panel discussion: afternoon speakers (07:21)
Closing remarks: (08:03)