@Jonathan Edwards I have been reading a lot and it seems as though most people with ME seem to go through a period of high immune response/ overactive followed by a decline or an underactive immune response.
Lipkin/ Hornig/ Petterson says this takes up to 3 years for the immune system to become exhausted which I feel is a more generalized figure probably an average.
I have been sick a year and present with low:
VEGF
CD3a and CD4a
High:
IL 10
CD13
TNF
TGF-Beta 1
Positive
ENA but not ANA
From what i was told my immune system is exhausted. I am not looking for a DX or med advice.
Why if they are finding ME patients with underactive immune systems would you want to use Rutux or Cyclo? My understanding these are immune system suppresents?
Further I read for one hard to treat Autoimmune disease that is deadly (I think it had to do with the skin) they used the combo of Rutuximab with IVIG with good success. Could this be a possibility for ME?
Possibly Belubimab with Low dose IVIG. Low dose IVIG may have worked for some ME Drs.
I am just throwing out things from what I have read but would like to hear your thoughts?