querying raw data in 23andme

[ebethc]

Can anyone tell me what "VERSION" means in 23andme?

In the Raw Data section, you can query a gene or SNP... The results show a table with the headers:
GENE, POSITION, SNP, VERSION, <NAME>'S GENOTYPE

So, for a particular gene BHLHE41 (with 3 snps) I got these results:

snp rs4963955, versions C or T, ebethc's genotype TT
snp rs4963956, versions C or T, ebethc's genotype CC
snp rs1480037, versions C or T, ebethc's genotype CC

Is the VERSION listed the bad result(s)? are BOTH C & T bad?

 

[Methyl Health]

Version is synonymous with "allele". It just tells you which alleles to expect in the genotype.

You cannot tell whether the the gene is a mutation or not on 23andme:

http://methylmutant.blogspot.com/p/hack-your-genes.html

 

[Valentijn]

C and T are the alleles (variations). Usually neither version has any impact, or just has a very small impact.

If you want to know if an allele can cause problems you need to look up the research regarding that SNP. http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs= is the best site I'm aware of. And typically a variation has to result in a missense mutation or a stop-gain (changes in the protein created) to have any real impact.

 

[Strawberry]

http://methylmutant.blogspot.com/p/hack-your-genes.html

The blog is gone? I am trying to find out how to access/use my data...

 

[Strawberry]

Awesome! Thank you! Is it worth the $40 or so to use the other one?

 

[Strawberry]

Yes, it was $20. I will post my results when I figure out how!