PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord

[Violeta]

https://thejournalofheadacheandpain...ng pathways can,needs further study in future.

• Binbin Wang, Siyuan Liu, Bingbing Fan, Xingguo Xu, Yonglin Chen, Rongxiang Lu, Zhongling Xu & Xiaojuan Liu 2018

Our findings demonstrate that inhibiting PKM2 expression effectively attenuates CCI-induced neuropathic pain and inflammatory responses in rats, possibly through regulating ERK and STAT3 signaling pathway