Phosphatidylcholine (PC) is a naturally occurring phospholipid molecule. It is the major lipid, or fat, of cell membranes and blood proteins. PC serves as the body’s main source of choline, an essential nutrient and precursor to the neurotransmitter, acetylcholine The terms "phosphatidylcholine" and "lecithin" are sometimes used interchangeably however, lecithin is actually a mixture of several lipids and phospholipid.
I got interested in another form of this, Delayed Release Phosphotidylcholine. Most PC products are soy or oil based which get digested and absorbed before reaching the large bowel which is where its beneficial effect takes place but this delayed version is derived from eggs (egg lecithin)
It's suggested as something to help with intestinal permeability and was in clinical trials in Germany for Ulcerative Colitis and something that Dr Myhill makes mention of (Endragil 500)
http://www.nature.com/ajg/journal/v109/n7/full/ajg2014104a.html
http://www.drmyhill.co.uk/wiki/Ulcerative_colitis_and_phosphatidylcholine_(PC)_in_the_gut
I don't think it has been released in the market place yet but the company producing this delayed version already has a similar product for sale as a supplement in European markets which is available at amazon.co.uk, PC Medicus Phosphatidylcholine by Medicus GmbH. It is only 30% PC strength as a coated granule though whereas the version in the clinical trials is 90% PC in capsules form. Earlier positive results from studies into this was only using concentration of 30% PC anyway so there is proved efficacy even at that concentration.
https://www.amazon.co.uk/Medicus-Gm...5031&field-lbr_brands_browse-bin=Medicus+GmbH
One of the co-inventors of this has suggested that as PC products need to get to the bowel intact to be of benefit, a lecithin retention enema could be just as effective.
If intestinal permeability is the major villain that it's made out to be in chronic GI dysfunction and if the the scientists behind these products are right in believing that PC depletion causes intestinal permeability, it stands to reason in my mind that this should be of benefit for those with other impaired motility issues where intestinal permeability is suspected to be a co-factor.