Opioids operate as pro-inflammatory cytokines, resulting in neuroinflammation in the CNS

pattismith

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I took morphine many years ago for severe fibromyalgia pain. Very soon after I started a very low dose, my ME/CFS got much, much worse. This could very well explain why.
I took two years Tramadol for neuropathic pain and got two years of major depression when I stopped.

Every time I take opioids on a regular basis, I feel very good the first day, and I feel like shit every days after... :xpem: