Have you considered using activated charcoal, 30-45 minutes after an antifungal to soak up the toxins being released? This if often extremely helpful in mitigating detox reactions.
I have tried activated charcoal but maybe im not taking enough. i always take it 30-45 minutes and it helps minimally. I take 250mg. However the antifungal I am currently on is by NOW foods Candida Clear. Charcoal also does constipate me so i'd rather have my bowels moving than take too much.
Getting the bowels moving daily and your first morning urine pH is in range can really assist with tolerance for detox as well. In Traditional Chinese Medicine, if the bowels are not moving daily, no progress can be made. Some things that can assist are oxypowder, aloe vera juice, high fiber foods, taurine, vitamin C, magnesium, or whatever you know works for you. Once this is established, it's appropriate to address the liver/kidney function. Liver Life and fresh squeezed lemons are great for this. You can test your first morning urine pH to see if you are draining acids efficiently, it should be acidic at 5.5-6.2. Once the bowels are moving daily, liver/kidney function is optmized and acids are draining efficiently, adding in detox agents will be much better tolerated as the organs of elimination are open and ready to filter the toxins efficiently. Aggravations during detox mean that you are getting rid of more toxins than the organs can comfortably excrete. So you optimize their function and start detox agents at a low dose ramping up as tolerated. And if you do give too high a dose and experience detox reactions, activated charcoal is an amazing way to mitigate the detox reactions. It soaks up those excess acids that are released.
I tried milk thistle at 75mg and had breathing issues. All my bad reactions to herbals manifest itself in a very very dizzy/brain fog followed by the inability to breath. It has nothing to do with my lungs, my lungs are clear and a PFT was perfect. It is something related to either allergic type but not full blown IgE attack or something else unrelated. The only clue I hve to this is that my pulse ox would drop when I continue treatment that isn't right for me AKA b12. And to dangerous levels I might add. Kind of scared to try liver life since it contains Milk thistle seeds. I guess I could try a dro p or two or a very low dose of it if it works. Better than nothing.
Hope this helps.
TamiW