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NSAIDS Significantly Inhibit Ovulation/Progesterone.

Ema

Senior Member
Messages
4,729
Location
Midwest USA
The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) show that diclofenac, naproxen and etoricoxib significantly inhibit ovulation in women with mild musculoskeletal pain. Of the women receiving NSAIDs, only 6.3 percent (diclofenac), 25 percent (naproxen) and 27.3 percent (etoricoxib) ovulated, compared with 100 percent of the control group.

These findings suggest that readily available non-steroidal anti-inflammatory drugs (NSAIDs) could have a harmful effect on fertility, and should be used with caution in women wishing to start a family.

'After just ten days of treatment we saw a significant decrease in progesterone, a hormone essential for ovulation, across all treatment groups, as well as functional cysts in one third of patients,' said study investigator Professor Sami Salman, Department of Rheumatology, University of Baghdad, Iraq. 'These findings show that even short-term use of these popular, over-the-counter drugs could have a significant impact on a women's ability to have children. This needs to be better communicated to patients with rheumatic diseases, who may take these drugs on a regular basis with little awareness of the impact.'

http://www.sciencedaily.com/releases/2015/06/150611082124.htm
 

Mya Symons

Mya Symons
Messages
1,029
Location
Washington
Interesting. I take diclofenac. I am not planning on having any more children; however, I am wondering what low progesterone will do to the body in the long run. I wonder if it is contributing to the osteoarthritis and the fibromyalgia?