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Nimodipine

Waverunner

Senior Member
Messages
1,079
Does anyone have any experience with Nimodipine? It's a calcium channel blocker and seems to have some positive effect on brain recovery after stroke for example. It has anti-inflammatory effects, it seems to modify BBB permeability and increases oxygen delivery to brain cells.

http://www.ugc.edu.hk/rgc/rgcnews19/eng/05.htm

"Nimodipine can inhibit the equilibrative nucleoside transporter type-1 (ENT-1) , thereby increasing the local concentration of adenosine in the vicinity of adenosine receptors on endothelial cells. The increased stimulation of adenosine receptors may be a mechanism underlying the anti-inflammatory effect of nimodipine."