Pyrrhus
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There is an upcoming NIH Conference:
"Beyond the Symptom: The Biology of Fatigue"
September 27 - 28, 2021
https://web.cvent.com/event/4630788...sitePage:645d57e4-75eb-4769-b2c0-f201a0bfc6ce
"Beyond the Symptom: The Biology of Fatigue"
September 27 - 28, 2021
https://web.cvent.com/event/4630788...sitePage:645d57e4-75eb-4769-b2c0-f201a0bfc6ce
Agenda
September 27-28, 2021
DAY 1: September 27, 2021
10:00 – 10:10 am Introductions and Welcome – Vicky Whittemore, PhD, NIH/NINDS and H. Craig Heller, PhD, Stanford
University & Sleep Research Society
10:10 – 10:20 am Goals of the Workshop – David Raizen, MD, PhD (University of Pennsylvania)
SESSION 1: Fatigue in the Setting of Disease
Moderators: Erin Gibson, PhD (Stanford University) and Anthony L. Komaroff, MD (Harvard Medical School)
10:20 – 10:40 am Acute to Chronic Infection - Josh Fessel, MD, PhD (NIH/NHLBI)
10:40 – 11:00 am Post-Cancer Treatment Fatigue – Leorey Saligan, PhD (NIH/NINR)
11:00 – 11:20 am Autoimmune Disorders – Lauren Krupp, MD (New York University)
11:20 – 11:40 am Exercise-induced Fatigue and Recovery – H. Craig Heller, PhD (Stanford University & Sleep
Research Society)
11:40 – 11:55 am Break
11:55 am – 12:15 pm ME/CFS – Betsy Keller, PhD (Ithaca College)
12:15 – 12:35 pm Altered Sensory (Proprioception, Vision and Audition) Processing: A Possible Common
Mechanism of Chronic Fatigue in Nurological Diseases - Anna Kuppuswamy, PhD
(University College London)
12:35 – 12:55 pm Sleep Disruption/Fragmentation – Phyllis Zee, MD, PhD (Northwestern University)
12:55 – 1:30 pm Session 1: Discussion
1:30 – 2:00 pm Break
SESSION 2: Theories for Mechanisms of Fatigue
Moderators: Nancy Klimas, MD (Nova Southeastern University) and Avindra Nath, MD (NIH/NINDS)
2:00 – 2:20 pm Brain->Immune Interactions - Asya Rolls, PhD (Technion – Israel Institute of Technology)
2:20 – 2:40 pm Immunomodulators as Regulators of Sleep and Fatigue - Mark Opp, PhD (University of Colorado)
2:40 – 3:00 pm Inflammation Effects on the Brain and Behavior: Relevance to Fatigue – Andrew H. Miller, PhD
(Emory School of Medicine)
3:00 – 3:20 pm Immune Dysfunction in ME/CFS - Maureen Hanson, PhD (Cornell University)
3:20 – 3:40 pm Molecular and Cellular Biology in ME/CFS – W. Ian Lipkin, MD (Columbia University)
3:40 – 3:55 pm Break
3:55 – 4:15 pm The Role of the Metabolic Trap in Fatigue - Ron Davis, PhD (Stanford University)
4:15 – 4:35 pm Neuron-glia Metabolic Coupling: Roles in Plasticity and Pathology - Pierre Magistretti, MD, PhD
(King Abdullah University of Science and Technology)
4:35 – 4:55 pm Gut-brain Axis – Gerard Clarke, PhD (University of Cork)
4:55 – 5:15 pm Reactive Oxygen Species in the Brain and in the Periphery - Dragona Ragulja, PhD (Harvard University)
5:15 – 5:35 pm Circadian Misalignment- Beth Klerman, MD, PhD (Harvard University)
5:35– 6:00 pm Session 2: Discussion
DAY 2 – September 28, 2021
10:00 – 10:10 am Introduction to Day 2 – Janet Mullington, PhD (Beth Israel Deaconess Medical Center & Harvard
Medical School)
10:10 – 10:25 am Comments from NINDS Director – Walter Koroshetz, MD (NIH/NINDS)
SESSION 3: Approaches to Study Fatigue
Moderator: Mary Harrington, PhD (Smith College)
10:25 – 10:55 pm Omics in Human Disease - Ron Tompkins, MD (Massachusetts General Hospital)
10:55 – 11:15 am GWAS: Use of the UKBB for Genetic Discovery – Richa Saxena, PhD (Massachusetts General Hospital
Center for Genomic Medicine)
11:15 – 11:25 am Use of EHR for Understanding Disease - Marilyn Richie, PhD (University of Pennsylvania)
11:25 – 11:45 am Electroencephalography of Non-refreshing Sleep – Janet Mullington, PhD (Beth Israel Deaconess
Medical Center & Harvard Medical School)
11:45 am – 12:00 pm Break
Models for Studying Fatigue
12:00 – 12:25 pm Approaches to Study the Biology of Fatigue in Preclinical Models - Robert Dantzer, DVM, PhD
(The University of Texas MD Anderson Cancer Center)
12:25 – 12:45 pm Use of LPS to Model Human Fatigue – Julie Lasselin, PhD (Stockholm University)
12:45 – 1:05 pm Pharmacology of Fatigue Behavior in Rodents - John Salamone, PhD (University of Connecticut)
1:05 – 1:25 pm Studying Hibernation Biology to Gain Insights into Fatigue – Kelly Drew, PhD (University of Alaska)
1:25 – 1:45 pm Studying Fatigued Behavior in Invertebrates - David Raizen, MD (University of Pennsylvania)
1:45 – 2:05 pm Session 3: Discussion
2:05 – 2:20 pm Break
SESSION 4: Neurobiology of Fatigue
Moderator: Cliff Saper, MD, PhD (Beth Israel Deaconess Medical Center & Harvard University)
2:20 – 2:40 pm Neuroimaging: PET, fMRI, MRS - Jarred Younger, PhD (University of Alabama at Birmingham)
2:40 – 3:00 pm Psychomotor Slowing – Professor Hugo Critchley (University of Sussex)
3:00 – 3:20 pm Evidence for a Network of Fatigue-Related Areas in the Brain – Glenn Wylie, DPhil
(Kessler Foundation)
3:20 – 3:40 pm Hypothalamus – Patrick Fuller, PhD (University of California, Davis)
3:40 – 4:00 pm The Role of the Brainstem in Slow-Wave-Sleep Control – Christelle Anaclet, PhD (University
of Massachusetts)
4:00 – 4:15 pm Break
4:15 – 4:35 pm Role of Glympathics in Sleep and Fatigue – Maiken Nedergaard, MD, DMSc (University of Rochester
Medical Center)
4:35 – 4:55 PM CSF Flow and Slow Wave Oscillations During Sleep – Laura Lewis, PhD (Boston University)
4:55 – 5:25 PM Session 4: Discussion
5:25 – 6:00 pm Workshop Wrap-up
