Lily
*Believe*
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"Work with the XMRV virus is "potentially explosively important," Sarafianos said........
http://bondlsc.missouri.edu/news/story/38/1
http://bondlsc.missouri.edu/news/story/38/1
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Thanks, Lily - the XMRV bit is in the right-hand sidebar on that page.
In this case, "solving the structure" means identifying the protein's three-dimensional detailed shape so accurately that researchers will be able to design a molecule which can bind tightly to that protein and potently block its biological activity, he said.
This kind of bespoke drug design has been talked about for decades but doing it in practice, and translating that into a safe and effective drug is a different matter; turns out this process is much harder than it sounds.
In this case, "solving the structure" means identifying the protein's three-dimensional detailed shape so accurately that researchers will be able to design a molecule which can bind tightly to that protein and potently block its biological activity, he said.
This kind of bespoke drug design has been talked about for decades but doing it in practice, and translating that into a safe and effective drug is a different matter; turns out this process is much harder than it sounds.