https://www.sciencedaily.com/releases/2022/09/220901135757.htm
"Scientists have discovered a new kind of synapse in the tiny hairs on the surface of neurons. The commonly overlooked protrusions called primary cilia contain special junctions that act as a shortcut for sending signals quickly and directly to the cell's nucleus, inducing changes to the cell's chromatin that forms chromosomes."
"Scientists had largely ignored these cilia because they were difficult to see with traditional imaging techniques. But recently, better imaging tools have sparked an interest in these tiny appendages."
Yet another discovery of an important body part that's been ignored/unknown until now. I think this is the third I've posted about in the last couple of years. What else is still hiding in our bodies, as potential targets of treatments?
In terms of ME, can anyone say that the root dysfunction of ME isn't in these cilia? Could the ratio of a specific amino acid and a specific fatty acid in the brain fluid cause subtle changes in the cilia functions, which in turn affect the neuron's functions, which in turn affects the rest of the body? We don't know, since no one's bothered to check them, and studies of blood or muscles won't reveal the answer if it's these hard-to-study cilia.
We need a Star-trek medical tricorder: it checks everything.
"Scientists have discovered a new kind of synapse in the tiny hairs on the surface of neurons. The commonly overlooked protrusions called primary cilia contain special junctions that act as a shortcut for sending signals quickly and directly to the cell's nucleus, inducing changes to the cell's chromatin that forms chromosomes."
"Scientists had largely ignored these cilia because they were difficult to see with traditional imaging techniques. But recently, better imaging tools have sparked an interest in these tiny appendages."
Yet another discovery of an important body part that's been ignored/unknown until now. I think this is the third I've posted about in the last couple of years. What else is still hiding in our bodies, as potential targets of treatments?
In terms of ME, can anyone say that the root dysfunction of ME isn't in these cilia? Could the ratio of a specific amino acid and a specific fatty acid in the brain fluid cause subtle changes in the cilia functions, which in turn affect the neuron's functions, which in turn affects the rest of the body? We don't know, since no one's bothered to check them, and studies of blood or muscles won't reveal the answer if it's these hard-to-study cilia.
We need a Star-trek medical tricorder: it checks everything.
