Neuroinflammation May Cause Mental Sluggishness

[pattismith]

Some of this data could indicate the presence of pain, there is quite a bit of pain in Fibro as well as in ME.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374269/

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or the high theta /alpha ratio may be signature for neuroinflammation (this quote is from an alzheimer 2017 paper)
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The index of theta/alpha ratio was significantly higher in patients with AD in comparison to healthy individuals

 

[pattismith]

SYSTEMATIC REVIEW article

Front. Psychiatry, 25 August 2020 | https://doi.org/10.3389/fpsyt.2020.00871
EEG for Diagnosis of Adult ADHD: A Systematic Review With Narrative Analysis
Marios Adamou1*,

Tim Fullen2 and Sarah L. Jones2

• 1School of Human & Health Sciences, University of Hudderfield, West Yorkshire, United Kingdom
• 2Adult ADHD & Autism Service, South West Yorkshire Partnership NHS Foundation Trust, Wakefield, United Kingdom

Results:

Differences in electroencephalogram activity are potentially unique to adult attention deficit hyperactivity disorder populations.

Strongest support was derived for elevated levels of both absolute and relative theta power, alongside the observation that alpha activity is able to typically differentiate between adult attention deficit hyperactivity disorder and normative populations.

It's interesting that some ADHD patients have a "sleepy" phenotype. It would be nice if these sleepy patients could have a separate subgroup in this kind of study!

However, the sleepiness in ADHD has not be fully explained...