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Need Assistance with results ...

Messages
4
Can anyone assist me with these results? With my limited knowledge I would have to guess that my methylation is fairly poor.

Health issues experienced at times

Strong anxiety / panic attacks
Chronic Fatigue, regardless of amount of sleep
Sexual "issues"
Poor sleep / night waking


Maybe someone can make sense of this? Thanks in advance.


Some of it is a bit concerning particularly:

COMT V158M rs4680 AA +/+ (4 COMT mutations = dopamine issue?)
COMT H62H rs4633 TT +/+

MTHFR C677T rs1801133 AA +/+
CBS C699T rs234706 AA +/+
BHMT-08 rs651852 TT +/+


CYP1B1 L432V rs1056836 GG +/+ (4 CYP1B1 mutations = Estrogen Issue?)
CYP1B1 R48G rs10012 CC +/+

Gene & VariationrsIDAllelesResult
COMT V158M rs4680 AA +/+
COMT H62H rs4633 TT +/+

COMT P199P rs769224 GG -/-
VDR Bsm rs1544410 CC -/-
VDR Taq rs731236 AA +/+
MAO A R297R rs6323 G -/-
ACAT1-02 rs3741049 GG -/-
MTHFR C677T rs1801133 AA +/+
MTHFR 03 P39P rs2066470 GG -/-
MTHFR A1298C rs1801131 TT -/-
MTR A2756G rs1805087 AA -/-
MTRR A66G rs1801394 AG +/-
MTRR H595Y not found
MTRR K350A rs162036 AG +/-
MTRR R415T not found
MTRR A664A rs1802059 GG -/-
BHMT-02 rs567754 CC -/-
BHMT-04 not found
BHMT-08 rs651852 TT +/+
AHCY-01 rs819147 CT +/-
AHCY-02 not found
AHCY-19 rs819171 CT +/-
CBS C699T rs234706 AA +/+
CBS A360A rs1801181 GG -/-
CBS N212N not found
SHMT1 C1420T not found
Profile: Methylation Profile
Generated: 10/22/2014
Download this report as a PDF:


Gene & Variation rsID Alleles Result

CYP1A1*2C A4889G rs1048943 TT -/-
CYP1A1 m3 T3205C rs4986883 TT -/-
CYP1A1 C2453A rs1799814 GG -/-
CYP1A2 164A>C rs762551 AA -/-
CYP1B1 L432V rs1056836 GG +/+
CYP1B1 N453S rs1800440 TT -/-
CYP1B1 R48G rs10012 CC +/+
CYP2A6*2 1799T>A rs1801272 AA -/-
CYP2A6*20 rs28399444 II -/-
CYP2C9*2 C430T rs1799853 CT +/-
CYP2C9*3 A1075C rs1057910 AA -/-
CYP2C19*17 rs12248560 CC -/-
CYP2D6 S486T rs1135840 CG +/-
CYP2D6 100C>T rs1065852 GG -/-
CYP2D6 2850C>T rs16947 AG +/-
CYP2E1*1B 9896C>G rs2070676 CC -/-
CYP2E1*1B 10023G>A rs55897648 GG -/-
CYP2E1*4 4768G>A rs6413419 GG -/-
CYP3A4*1B rs2740574 TT -/-
CYP3A4*2 S222P rs55785340 AA -/-
CYP3A4*3 M445T rs4986910 AA -/-
CYP3A4*16 T185S rs12721627 GG -/-
GSTP1 I105V rs1695 AA -/-
GSTP1 A114V rs1138272 CC -/-
SOD2 A16V rs4880 AA -/-
NAT1 R187Q rs4986782 GG -/-
NAT1 R64W rs1805158 CC -/-
NAT2 I114T rs1801280 CT +/-
NAT2 R197Q rs1799930 GG -/-
NAT2 G286E rs1799931 GG -/-
NAT2 R64Q rs1801279 GG -/-
NAT2 K268R rs1208 GG +/+


Sterling App

DETOX
Gene & VariationrsID #Risk AlleleYour Alleles & Results
CYP1A1*2C A4889G rs1048943 C TT -/-
CYP1A1*4 C2453A rs1799814 T GG -/-
CYP1A2 C164A rs762551 C AA -/-
CYP1B1 L432V rs1056836 C GG -/-
CYP1B1 N453S rs1800440 C TT -/-
CYP1B1 R48G rs10012 C CC +/+
CYP2A6*2 A1799T rs1801272 T AA -/-
CYP2C19*17 rs12248560 T CC -/-
CYP2C9*2 C430T rs1799853 T CT +/-
CYP2C9*3 A1075C rs1057910 C AA -/-
CYP2D6 S486T rs1135840 G CG +/-
CYP2D6 T100C rs1065852 A GG -/-
CYP2D6 T2850C rs16947 A AG +/-
CYP2E1*1B G9896C rs2070676 G CC -/-
CYP2E1*4 A4768Grs6413419AGG-/-
CYP3A4*1Brs2740574CTT-/-
CYP3A4*3 M445Trs4986910GAA-/-
GPX3rs8177412C
GSTM1rs12068997T
GSTM1rs4147565A
GSTM1rs4147567G
GSTM1rs4147568A
GSTM1rs1056806TCC-/-
GSTM1rs12562055A
GSTM1rs2239892G
GSTP I105Vrs1695GAA-/-
GSTP1 A114Vrs1138272TCC-/-
NAT1 A560G(?) (R187Q)rs4986782AGG-/-
NAT2 A803G (K268R)rs1208GGG+/+
NAT2 C190T (R64W)rs1805158TCC-/-
NAT2 G590A (R197Q)rs1799930AGG-/-
NAT2 G857A (G286E)rs1799931AGG-/-
NAT2 T341C (I114T)rs1801280CCT+/-
SOD2rs2758331ACC-/-
SOD3rs2855262TTT+/+
SOD2 A16Vrs4880GAA-/-
PON1 Q192Rrs662CCC+/+

TONGUE TIE / CLEFT PALATE

CTH S4031Irs1021737TGG-/-
IRF6rs987525ACC-/-
IRF6rs861020AGG-/-
RARArs7217852GAA-/-
RARArs9904270T
TBX22rs41307258AT-
TBX22rs28935177TA-

ALLERGY/MOLD

HLArs7775228CTT-/-
HLArs2155219TGG-/-

IgE

FCER1Ars2427837A
IL-13 C1112Trs1800925TCT+/-
DARCrs2814778CTT-/-
IL13rs1295685A
CD14rs2569191CCT+/-
SOCS-1 -820G>Trs33977706AAC+/-
C3rs366510G
FCER1A / OR10J2Prs2494262A
FCER1Ars2251746CCT+/-
RAD50rs2040704GAG+/-
RAD50rs2240032TCT+/-

IgG

FCGR2Ars1801274AGG-/-
GSTM3 V224Irs7483TTT+/+
TNFRSF13Brs4792800G

IgA

TRAF1rs3761847GGG+/+
IRF5rs4728142AAA+/+
IGF1Rrs2229765AAG+/-
IFIH1 (HLA)rs1990760CCC+/+
HLArs9271366GAA-/-
CFHrs6677604AAG+/-
HLA-DQA2rs9275224AAA+/+
MTC03P1rs9275596CCT+/-
PSMB8 / TAP1 / TAP2rs9357155AGG-/-
HLA-DPB2 / COL11A2Prs1883414AAG+/-

CLOTTING FACTORS

CETPrs1800775CCC+/+
CYP4V2rs13146272CCC+/+

GP6rs1613662GAG+/-
ITGB3 T196Crs5918CCT+/-
KNG I598Trs2731672TCC-/-
NR1I2rs1523127CAC+/-
SERPINC1rs2227589TCC-/-
HRGrs9898TCC-/-
F12rs1801020A
F11rs2289252TTT+/+
F11rs2036914T
F10 113777509rs3211719GAA-/-
F7 A353Grs6046AAG+/-
F2 (Prothrombin 20210A)i3002432AGG-/-
F3 94997288rs1324214A
F5 (Factor V Leiden)rs6025TCC-/-
F9 G580Ars6048GA-

METHYLATION

ACE Del16rs4343GAG+/-
ADD1 G460Wrs4961TGG-/-
ACAT1-02rs3741049AGG-/-
AGT M235T/C4072Trs699GAG+/-
AHCY-01rs819147CCT+/-
AHCY-02rs819134G
AHCY-19rs819171CCT+/-
BHMTrs16876512T
BHMTrs6875201GAA-/-
BHMT-02rs567754TCC-/-
BHMT-04rs617219C
BHMT-08rs651852TTT+/+
BHMT R239Qrs3733890AGG-/-
CBS A13637Grs2851391TTT+/+
CBS A360Ars1801181AGG-/-
CBS C19150Trs4920037AAA+/+
CBS C699Trs234706AAA+/+

CBS N212Nrs2298758A
COMTrs6269GAA-/-
COMT -61 P199Prs769224AGG-/-
COMT H62Hrs4633TTT+/+
COMT V158Mrs4680AAA+/+

DAOrs2070586AGG-/-
DAOrs2111902G
DAOrs3741775CAC+/-
DHFRrs1643649CTT-/-
FOLR1rs2071010AGG-/-
FOLR2rs651933AAG+/-
FOLR3rs7925545GAA-/-
FOLR3rs7926875A
FUT2rs492602GAA-/-
FUT2rs601338AGG-/-
FUT2rs602662AAG+/-
G6PDrs1050828TC-
G6PDrs1050829CT-
GAD1rs3749034AGG-/-
GAD1rs2241165CTT-/-
GAD1rs769407CCC+/+
GAD1rs2058725CTT-/-
GAD1rs3791851CCC+/+
GAD1rs3791850AGG-/-
GAD1rs12185692ACC-/-
GAD1rs3791878TTT+/+
GAD1rs10432420AGG-/-
GAD1rs3828275TCC-/-
GAD1rs701492TTT+/+
GAD1rs769395G
GAD2rs1805398T
GAMTrs17851582AGG-/-
GAMTrs55776826TCC-/-
GIF (TCN3)rs558660AGG-/-
MAO A R297Rrs6323TG-
MAT1Ars72558181T
MTHFD1 C105Trs1076991CCT+/-
MTHFD1 G1958Ars2236225AGG-/-
MTHFD1Lrs11754661AGG-/-
MTHFD1Lrs17349743CCT+/-
MTHFD1Lrs6922269AAG+/-
MTHFD1Lrs803422AGG-/-
MTHFR 03 P39Prs2066470AGG-/-
MTHFR A1298Crs1801131GTT-/-
MTHFR A1572Grs17367504GAA-/-
MTHFR C677Trs1801133AAA+/+
MTHFR G1793A (R594Q)rs2274976TCC-/-
MTHFRrs12121543A
MTHFRrs13306560TCC-/-
MTHFRrs13306561G
MTHFRrs1476413TCC-/-
MTHFRrs17037390AGG-/-
MTHFRrs17037396T
MTHFRrs3737964TCC-/-
MTHFRrs4846048GAG+/-
MTHFRrs4846049TGG-/-
MTHFSrs6495446CCC+/+
MTR A2756Grs1805087GAA-/-
MTRR A66Grs1801394GAG+/-
MTRR H595Yrs10380T
MTRR K350Ars162036GAG+/-
MTRR R415Trs2287780T
MTRR-11 A664Ars1802059AGG-/-
MTRRrs10520873C
MTRRrs1532268TCC-/-
MTRRrs162049G
MTRRrs3776467GAG+/-
MTRRrs9332AAG+/-
NOS1rs3782206T
NOS2rs2297518AAG+/-
NOS2rs2274894TGT+/-
NOS2rs2248814AAG+/-
NOS3rs1800783ATT-/-
NOS3rs1800779GAA-/-
NOS3rs3918188AAC+/-
NOS3 G10Trs7830T
NOS3 T786Crs2070744C
PEMTrs4244593TGT+/-
PEMTrs4646406AAT+/-
PEMTrs7946CCT+/-
SHMT1 C1420Trs1979277A
SHMT1rs9909104C
SHMT2rs12319666T
SHMT2rs34095989AAG+/-
SLC19A1rs1888530T
SLC19A1rs3788200A
TCN1rs526934GAA-/-
TCN2 C766Grs1801198GCC-/-
TYMSrs502396C
VDR Bsmrs1544410TCC-/-

CELIAC DISEASE/GLUTEN INTOLERANCE

HLArs2858331GAA-/-
HLA DQA1rs2187668TCT+/-

THYROID

CTLA4rs231775GAG+/-
FOXE1rs1867277AGG-/-
FOXE1rs7043516C
FOXE1rs10984009AGG-/-
EYE HEALTH
Gene & VariationrsID #Risk AlleleYour Alleles & Results
BCMO1rs4889294CTT-/-
BCMO1 R267Srs12934922TAA-/-
BCMO1 A379Vrs7501331TTT+/+

MITOCHONDRIAL FUNCTION

ATP5g3rs185584G
ATP5g3rs36089250CTT-/-
ATP5c1rs2778475A
ATP5c1rs1244414TCT+/-
ATP5c1rs1244422T
ATP5c1rs12770829T
ATP5c1rs4655C
COX5Ars8042694GAA-/-
COX6Crs4626565CCC+/+
COX6Crs7844439A
COX6Crs4510829A
COX6Crs1135382A
COX6Crs7828241C
COX6Crs12544943G
COX6Crs4518636C
NDUFS3rs2233354C
NDUFS3rs4147730AAG+/-
NDUFS3rs4147731A
NDUFS7rs2332496AAA+/+
NDUFS7rs7254913G
NDUFS7rs1142530TTT+/+
NDUFS7rs7258846TTT+/+

NDUFS7rs11666067A
NDUFS7rs2074895A
NDUFS7rs809359GAA-/-
NDUFS8rs4147776C
NDUFS8rs1122731A
NDUFS8rs999571AGG-/-
NDUFS8rs2075626CTT-/-
NDUFS8rs3115546G
NDUFS8rs1104739C
NDUFS8rs1051806TCC-/-
UQCRC2rs6497563C
UQCRC2rs4850AGG-/-
UQCRC2rs11648723T
UQCRC2rs12922362A
UQCRC2rs2965803T

OTHER IMMUNE FACTORS

4q27 Regionrs6822844TGG-/-
APOErs429358CTT-/-
ATG16L1rs10210302TCT+/-
GSDMBrs7216389TCT+/-
HLA-DRB1rs660895GAA-/-
IL5rs2069812AGG-/-
IL-13rs20541AAA+/+
IL4R Q576Rrs1801275GAA-/-
MeFV A744Si4000409ACC-/-
MeFV E148Qrs3743930GCC-/-
MeFV F479Li4000403CGG-/-
MeFV K695Ri4000407CTT-/-
MeFV M680Irs28940580GCC-/-
MeFV M694Irs28940578TCC-/-
MeFV M694Vi4000406CTT-/-
MeFV P369Srs11466023AGG-/-
MeFV R761Hi4000410TCC-/-
STAT4rs10181656GCC-/-
TNF -308rs1800629AAG+/-
TNF -238rs361525AGG-/-
TYR (MeFV) V726Ars28940879AGG-/-

SULFONOTRANSFERASE

SULT1A1rs35728980GGT+/-
SULT1A1rs1801030C
SULT1A1rs1042157AAG+/-
SULT1A1rs36043491TCC-/-
SULT1A1rs60749306CTT-/-
SULT1A1rs9282862CTT-/-
SULT1A1rs1042008AGG-/-
SULT1A1rs2925627C
SULT1A1rs2925631C
SULT1A1rs3020800G
SULT1A1rs4149385TCC-/-
SULT1A1rs60701883ACC-/-
SULT1A1rs4149381GTT-/-
SULT1A1rs8057055A
SULT1A1rs6498090A
SULT1A1rs7193599C
SULT1A1rs7192559TCC-/-
SULT1A3rs1059667A
SULT2A1rs296366TCT+/-
SULT2A1rs296365C
SULT2A1rs11569679TCC-/-
SULT2A1rs4149452TCC-/-
SULT2A1rs8113396G
SULT2A1rs2547242C
SULT2A1rs2910393T
SULT2A1rs4149449TCC-/-
SULT2A1rs2547231CAC+/-
SULT2A1rs4149448G
SULT2A1rs11083907AGG-/-
 
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