My body wants estrogen, dislikes progesterone - conundrum


Senior Member
Any updates on this old thread? I've just worked out that 6 years of pain and intense fatigue could possibly be related to massive doses of progesterone I took for my IVF cycles. Or progesterone stored in my fat, Or just being very intolerant to progesterone. Have just started HRT hormones just this last week and while the estrogen patch feels great, the moment I take the tiniest amount of progesterone, my fibro symptoms come back worse than ever within a matter of hours.

Yes, you are not alone, I am one of very few women who are considered progesterone intolerant or over sensitive, which are diagnosed by equally few endo specialists. All my illness started from my first menstruation since I was 12 till today.
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