My allergies dissapeared in Spain. Why?

SWAlexander

Senior Member
Messages
2,232
I have been to a lot of places and around thousands of people but never knew anyone else.
Many people live with Post-Polio Syndrome (PPS), yet few speak openly about it.

They’re often worn down by stigma or frustrated by a constant stream of misguided advice—whether from well-meaning individuals armed with “magazine wisdom,” or even medical professionals unfamiliar with the pathophysiology of PPS, who wrongly assume that exercise is the solution.

That’s why I wrote this science-based explanation:

Initial Damage:

During the acute phase of poliovirus infection, motor neurons in the spinal cord and brainstem are damaged or destroyed.

Compensatory Mechanism:
The surviving neurons respond by sprouting new terminal branches—a process known as collateral sprouting—to reinnervate the affected muscle fibers. This leads to the formation of enlarged “giant motor units.”

Progressive Decline:
Decades after initial recovery, these overburdened motor neurons begin to fail. Their progressive degeneration results in renewed denervation of muscle fibers.

Why Symptoms Return:
At this stage, the body’s compensatory mechanisms—such as acetylcholine synthesis and further sprouting—can no longer keep up. The result is increasing muscle weakness, fatigue, and the hallmark symptoms of Post-Polio Syndrome.
 
Last edited:

I am sick

Senior Member
Messages
293
Many people live with Post-Polio Syndrome (PPS), yet few speak openly about it.

They’re often worn down by stigma or frustrated by a constant stream of misguided advice—whether from well-meaning individuals armed with “magazine wisdom,” or even medical professionals unfamiliar with the pathophysiology of PPS, who wrongly assume that exercise is the solution.

That’s why I wrote this science-based explanation:

Initial Damage:

During the acute phase of poliovirus infection, motor neurons in the spinal cord and brainstem are damaged or destroyed.

Compensatory Mechanism:
The surviving neurons respond by sprouting new terminal branches—a process known as collateral sprouting—to reinnervate the affected muscle fibers. This leads to the formation of enlarged “giant motor units.”

Progressive Decline:
Decades after initial recovery, these overburdened motor neurons begin to fail. Their progressive degeneration results in renewed denervation of muscle fibers.

Why Symptoms Return:
At this stage, the body’s compensatory mechanisms—such as acetylcholine synthesis and further sprouting—can no longer keep up. The result is increasing muscle weakness, fatigue, and the hallmark symptoms of Post-Polio Syndrome.
That has to be the best article I have read ! Your Q&A was fabulous!
I normaly cant stay focused on long articles but for some reason I could follow it effortlessly. Thank you.

As a whole people have changed and lost Empathy.
Where we live now their are some of the nicest people We have ever met.

But if something appears wrong with you they treat you like you have the plague! A few dont but the majority does.

When my Dr put me on high flow oxygen to see if it helped my Cfs people would avoid me , when I used a wheel chair for my post stroke evaluation people would look away or give me a wide berth!

Now if a person in front or behind me was on cruches with a big leg or foot brace they would do every thing to help them!

People used to stop and help others if they were beside the road broke down or have a flat tire and help change it , but now they just fly by!

Even with my chronic fatigue I still stop and change peoples tires or wait in my vehicle untill someone shows up to provide professioal help.
Its just the right thing to do for me.

I cant help your sickness , but I can be here if you just need someone to talk to.
 

SWAlexander

Senior Member
Messages
2,232
I can be here if you just need someone to talk to.
You are very kind, thank you.

Please understand, I'm neither lonely nor bored. What I truly need is more time in the day to write critical reviews (making enemies in the process), keep up with the latest research, and respond to the many questions I receive.

For example, people often reach out asking for help understanding their blood test results, because their primary care physicians don’t take the time to explain them.

My volunteer work keeps me busy every day. As long as I can support my elbows while typing—due to muscle weakness—I try to help where I can and raise awareness.

Here’s one example:

A 60-year-old woman I’ve known for two years was dealing with severe sleep disturbances, weakness, irritability, poor concentration, and prolonged PEM.
She was prescribed vitamin B12, but her symptoms didn’t improve.

Eventually, she had a more comprehensive lab test, which concluded:

"Functional B12 deficiency despite possibly normal serum B12 levels."

But the doctor didn’t review the rest of her results, which showed:
DHA significantly below the reference range in all three measurements

Omega-3 index <0.02% → extremely low Critically low levels of B6 and B3

Fatty acid imbalance with unfavorable distribution (e.g., DHA ↓)

Her doctor never asked about her diet—nor had I, until the lab results prompted me to. When I finally did, she revealed that she’s a vegetarian.
 

I am sick

Senior Member
Messages
293
You are very kind, thank you.

Please understand, I'm neither lonely nor bored. What I truly need is more time in the day to write critical reviews (making enemies in the process), keep up with the latest research, and respond to the many questions I receive.

For example, people often reach out asking for help understanding their blood test results, because their primary care physicians don’t take the time to explain them.

My volunteer work keeps me busy every day. As long as I can support my elbows while typing—due to muscle weakness—I try to help where I can and raise awareness.

Here’s one example:

A 60-year-old woman I’ve known for two years was dealing with severe sleep disturbances, weakness, irritability, poor concentration, and prolonged PEM.
She was prescribed vitamin B12, but her symptoms didn’t improve.

Eventually, she had a more comprehensive lab test, which concluded:

"Functional B12 deficiency despite possibly normal serum B12 levels."

But the doctor didn’t review the rest of her results, which showed:
DHA significantly below the reference range in all three measurements

Omega-3 index <0.02% → extremely low Critically low levels of B6 and B3

Fatty acid imbalance with unfavorable distribution (e.g., DHA ↓)

Her doctor never asked about her diet—nor had I, until the lab results prompted me to. When I finally did, she revealed that she’s a vegetarian.
Hi
Thank you,
You are very kind, thank you.
That is something I am not use to hearing! But I have been trying to improve myself.
You are Honorable in helping others!
Making enemies is all part of it!
It means you are doing the right things!

I know some vegans that are real healthy but the also know vegetables dont have the same vitamins and minearls they had ten years ago due to soil depletion and the other growing methods that make them almost devoid of any nutrients, so they adjusted by growing thier own.
And they will sneak in some meats at times!
Keep up the Great Work!
 
Back