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Mitochondrial transplant

Wishful

Senior Member
Messages
5,751
Location
Alberta
We don't even know whether mitochondrial dysfunction is a core part of ME. Besides, the abstract was about experiments with tissue samples, not human patients, so it's not a near-term option.
 

RYO

Senior Member
Messages
350
Location
USA
Research by Maureen Hanson and NIH intramural study does suggest decrease in mitochondrial function after exercise challenge in their patient cohort.

The purpose of my post was to promote/brainstorm potential treatment ideas.
 

Learner1

Senior Member
Messages
6,305
Location
Pacific Northwest
Are mitochondria damaged during acute severe viral infection?
https://pubmed.ncbi.nlm.nih.gov/34035362/
Dr. Prusty's work has shown that mitochondria are fragmented by herpesviruses.
Could mitochondrial transplantation be a potential treatment for MECFS patients?
Your article discusses primary mitochondrial diseases, which are genetic. I have seen four different mitochondrial specialists, because my testing has shown abnormal mitochondrial function. No one can find a genetic cause, but they do believe that my chemo drugs did damage my mitochondria. No one knows what to do with secondary mitochondrial dysfunction, although by far it is more common than primary mitochondrial diseases and is the basis for many diseases of aging.

As it is very difficult to get into any mitochondrial specialist, and if you do, to get anyone to help in any way, It's very unlikely that anyone would offer the treatment.

We have a multitude of mitochondria in cells. Depending on what kind of cell, the number of varies, but it can be into the thousands within a cell. Trying to transplant mitochondria into every one of your cells, or even a fair proportion is an unlikely proposition in the near future.

I have had a lot of help from using the strategies in the attached.
 

Attachments

  • Mitochondrial_Correction Dagostino Seyfried Riordan Nicolson.pdf
    421.7 KB · Views: 17

Wishful

Senior Member
Messages
5,751
Location
Alberta
Trying to transplant mitochondria into every one of your cells, or even a fair proportion is an unlikely proposition in the near future.

I was thinking about that too. Replacing mitochondria in the various brain cells would most likely be very difficult.