Ninan
Senior Member
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Anyone tried Orstanorm for OI? Minodrine isn't available where I live.
How does Midodrine differ from Florinef? I am currently taking 1/4 Florinef per day for tachycardia (IST/POTS type symptoms) as well as Atenolol. Sorry if this has already been explained !
http://www.drugs.com/mtm/florinef-acetate.htmlFludrocortisone is in a class of drugs called steroids.
http://www.rxlist.com/proamatine-drug.htmVasopressor/Antihypotensive
Thanks @Sushi! So would you say that Florinef is to raise blood volume/stop tachycardia and Midodrine is to constrict the veins and raise blood pressure?
Are you taking just the midodrine, or are you taking Florinef as well? My daughter takes both and is doing well -- doesn't have hypotension or a recurrence of migraines. If your before-moving-around--in-the-morning BP is 120/75, then perhaps Florinef is not indicated, but if your pre-Midodrine, pre-moving around pulse pressure is lowish, then it might be worth asking about adding a small Florinef dose.For those who are considering Midodrine - I'm 3 weeks in, 5mg 3-4 times per day depending on schedule.
The good:
1. HUGE appetite! I actually craved, ate, and digested a salad. Haven't done that in about 3 years.
2. Sleep seems better and I'm remembering dreams.
3. Stable BP, around 120/75
4. Side effects are waning.
5. Able to be on my feet a bit more without tachycardia, but still get tired really fast - actually rode along to the corner grocer with daughter and shopped for a few minutes!!!!! Haven't done that for a long time. (resulted in severe PEM, trying to find a balance.)
6. I can breathe thru my nose - in fact, that's how I can best gauge when I need next dose of midodrine.
The not-so-good:
1. Rebound hyPOtension seems worse! This morning it was 78/42. I felt like crap.
2. When my last dose of the day wears off, my migraines increase.
3. No change in brain fog.
The effect seemed cumulative for the first couple of weeks and has now leveled off.
Good to know. Thanks!!! My pre-midodrine BP is low - today it was 78/42.Are you taking just the midodrine, or are you taking Florinef as well? My daughter takes both and is doing well -- doesn't have hypotension or a recurrence of migraines. If your before-moving-around--in-the-morning BP is 120/75, then perhaps Florinef is not indicated, but if your pre-Midodrine, pre-moving around pulse pressure is lowish, then it might be worth asking about adding a small Florinef dose.
She takes 0.1mg of Florinef in the morning. She also fluid-loads with electolyte water before bed and first thing in the morning. I don't really know about covering between Midodrine doses, but it sounds likely since Florinef has a biological half-life of 18-36 hrs.Good to know. Thanks!!! My pre-midodrine BP is low - today it was 78/42.
Do you know your daughter's dose of Florinef? I'm glad she's doing so well. The first time I tried it, I got kidney pain and it scared me - but I'm willing to retry since I'm under the care of a (great!) nephrologist. It sounds like it levels out the blood volume enough to "cover" during the lapses in Midodrine?
@SDSue,
Are you taking anything for HR control yet? Might that help? You might be able to take less of the midodrine that way...?
My BP climbs for up to 6 weeks after I PEM myself. Could that be the reason for your BP spike? If so, you might be able to go back on the midodrine once you get over the crash.