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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/CFS (Fluge et al., 2016)

Wishful

Senior Member
Messages
5,796
Location
Alberta
It's not black and white.

Yes, and fatigue is not all one thing. We don't even have a clear, definite understanding of fatigue, with clinical tests to measure the different types accurately. The wiki definition includes three known causes of physical fatigue, not even considering cognitive fatigue. My point was that a title of a paper, or even the whole paper, might be misleading if they don't define fatigue clearly.
 

Learner1

Senior Member
Messages
6,305
Location
Pacific Northwest
Yes, and fatigue is not all one thing. We don't even have a clear, definite understanding of fatigue, with clinical tests to measure the different types accurately. The wiki definition includes three known causes of physical fatigue, not even considering cognitive fatigue. My point was that a title of a paper, or even the whole paper, might be misleading if they don't define fatigue clearly.
Agreed.