I'm surprised there's no way to medically "force down" one's cortisol or epinephrine just for a few days. I understand why drugs that do this permanently, like for Cushing's Disease, are dangerous if you don't have Cushing's, but why can't there be treatments just to lower these chemicals down temporarily? I feel like it would at least give the patient information about whether or not high cortisol, or cortisone, or epinephrine, is causing their CFS symptoms.
meds for high cortisol?
- Thread starter Merrick
- Start date
heapsreal
iherb 10% discount code OPA989,
- Messages
- 10,230
- Location
- australia (brisbane)
Phosphatidyle serine(PS) can help lower cortisol. Several years back i used PS at night and it did help improve sleep. I took 500mg a night. I did have a 24hr cortisol test and my night time cortisol was above the normal range at night and below the range in the morning.
Optimising dhea levels can help balance out the negative effects of high cortisol. Cortisol being a catabolic hormone and dhea being an anabolic hormone, we need the correct balance.
Optimising dhea levels can help balance out the negative effects of high cortisol. Cortisol being a catabolic hormone and dhea being an anabolic hormone, we need the correct balance.
Mary
Moderator Resource
- Messages
- 18,062
- Location
- Texas Hill Country
@Merrick - there's another product called Seriphos, which is phosphorylated serine - different from phosphatidyl serine though the names are confusingly similar. Some 20 years ago I had my cortisol levels checked, probably the same testing @heapsreal had - it was called the Adrenal Stress Index Test and used 4 saliva samples taking during the day/evening. My nighttime cortisol was quite high, when it was supposed to be low. And I had severe insomnia which nothing would touch.
I was told to take Seriphos and it worked like magic. I had to experiment to get the right dose and titrated up until I got results. I ended up needing a very high dose - 8 capsules a day, taken in the morning. I took 4 before breakfast and 4 late morning and started sleeping better almost immediately. Eventually I titrated down and now I take it occasionally as needed, but never that high of a dose again.
If you read the reviews, many say that Seriphos works better than plain phosphatidyl serine. But I think they both can help.
I was told to take Seriphos and it worked like magic. I had to experiment to get the right dose and titrated up until I got results. I ended up needing a very high dose - 8 capsules a day, taken in the morning. I took 4 before breakfast and 4 late morning and started sleeping better almost immediately. Eventually I titrated down and now I take it occasionally as needed, but never that high of a dose again.
If you read the reviews, many say that Seriphos works better than plain phosphatidyl serine. But I think they both can help.
Thank you for the reply. I don't think I have POTS. I've tried Clonidine. Unfortunately, it didn't do anything for me.
Hmm, I suppose at least that means you can eliminate excess catecholamines, although I’m not an expert on the topic. It was looked at briefly when I first saw an autonomic specialist, and they weren’t high, so I never read much on the topic. (I turned out to have a dfifferent type of orrthostatic intolerancce, not POTS.)
Oh, I just remembered that dexamethasone suppresses cortisol. But there’s always the risk of glucocorticoids causing adrenal insufficiency, so you’d have to factor that in if you decided to experiment.
I had a brush with adrenal insufficiency earlier this year after taking a short course of steroids for an itching attack. Very unpleasant. Luckily for me it resolved.
And sometimes people feel better on glucocorticoids because they damp down inflammation or autoimmune stuff, so it would be hard to know which effect was responsible if you did feel better, I suppose.
I had a brush with adrenal insufficiency earlier this year after taking a short course of steroids for an itching attack. Very unpleasant. Luckily for me it resolved.
And sometimes people feel better on glucocorticoids because they damp down inflammation or autoimmune stuff, so it would be hard to know which effect was responsible if you did feel better, I suppose.