I have read of many people here getting LPS and zonulin blood testing done but I haven't done it myself. So those tests are available.
Since you have been so kind to bring this to our attention, perhaps you could help by figuring out what tests they are.
@unicorn7 says she had a cd14 test done, it’s a marker for LPS in your blood. Zonulin is a marker for leaky gut.
So, looks like ARUP labs will do CD14.
Zonulin is one marker of leaky gut, so are multiplying food allergies, digestive issues, skin problems like eczema, and nutrient deficiencies.
The only other things that I'm doing is taking daily anti-microbial herbs like oil of oregano, holy basil, thyme, olive leaf extract etc. and numerous supplements to help heal my gut.
My view is that I have to get the bacteria re-balanced in my gut to bring down the inflammation, both in my gut and systemic inflammation, so my gut can heal.
It feels like that's what's happening, even though I can only tolerate fairly small amounts of anti-microbial herbs. I am definitely getting healthier!
Glad it's working for you. But, it is not the same for everyone.
Let's think about that statement - antimicrobial herbs. Which microbes are bring killed? These gut microbes work together in communities. Some support or complement each other. Some kill others off. Your interventions may just be the perfect thing for you but a disaster for someone else.
Diet and prebiotics I don't think will be enough for most people with ME/CFS. Anti-microbial herbs and supplements to heal the gut will also be necessary.
One must remove food allergens and foods with pesticides like RoundUp and toxins. And Candida, parasites, and viruses. One needs to restore the gut lining - glutamine and glycine can be helpful, while supporting phospholipids for cell membranes. Then supplying prebiotics and high quality probiotics.
It helps to know if you have bad actors in your gut and target interventions that kill things, like antimicrobial herbs ONLY if you have something thst needs killing.
However, it's not that easy. It can take many months of work to restore a microbiome. And no one knows what a perfect microbiome looks like. The science is not there.
And, even if one has a gut in good shape, one can still be sick. When I was at my sickest 2 years ago, sleeping 16 hours a day and unable to think straight and see straight, my dictir said i had one of the best looking stiol tests he'd ever seen. Now, however, whrn im doing much better, after 2 months of oral antibiotics, 4 months of IV antibiotics, and 3 months of 350 billion probiotics with herbal supplements and multiple high quality prebiotics, my gut has low diversity and the probiotics don't seem to be doing much. But im much more functional.
We are heterogeneous in this disease. The LPS theory is very interesting, but we need actionable information we can use.
If you find LPS with a CD14 test, then what?? What if you have bacterial translocation? Can you fix it? Fixing the gut is one issue, but this seems to be travelling into new territory. The info is not much use unless we can act on it and it changes our outcome...