ME/CFS and Interferon alpha

[HTester]

Has anyone on PR (or anyone you know) come down with ME/CFS while being treated with interferon alpha for a chronic infection?

Thanks for any help.

 

[Hip]

I have not come across a case of ME/CFS being triggered by interferon over my ten years on this forum.

 

[wigglethemouse]

Here are the threads with interferon in the title.
https://forums.phoenixrising.me/search/352725/?q=interferon&c[title_only]=1&o=date

I had a look through and the only thing useful I found were a few threads debating the usefulness or not of the Carmine Pariante's MRC funded study on persistent fatigue induced by interferon-alpha as a possible model for CFS. Tuller wrote a blog about it.
https://www.virology.ws/2019/01/07/trial-by-error-more-thoughts-on-the-interferon-study/

There is a long thread on s4me about that study too............
https://www.s4me.info/threads/persi...ic-fatigue-syndrome-2018-pariante-et-al.7050/

 

[HTester]

Thanks to you both.

 

[Dufresne]

I'm very surprised we haven't heard about cases of this. Stimulating cellular immunity is what messes me up the most. It brings me from a relatively mild case to housebound in a matter of weeks. It plays out very much like interferon induced depression and lasts months. But it only happens when cellular immunity is stimulated in the brain. Babesia treatment isn't a problem.