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MCAS and ANA

notmyself

Senior Member
Messages
364
hi, sorry for the off topic since is not about ME/CFs, but here is the only section i can post ..Would ANA will be elevated in MCAS or any mast cell disorder?! since ANA is showing autoimunity
 

Lisa108

Senior Member
Messages
675
since ANA is showing autoimunity
Just to split some hairs:
If you have ANAs, you very likely have an autoimmune disease. (Although some healthy people/elderly people will show ANAs, too).
But not all autoimmune diseases are caused by ANAs, as these are just one type of autoantibodies.
For example, in Hashimoto (an autoimmune disease), you won't find ANAs, but TPO and/or TG (auto)antibodies.

A list of autoimmune diseases associated with ANAs is here.
 

notmyself

Senior Member
Messages
364
i don't have ANA, not even close...that's the thing..i kinda suspect MCAS but just don t want to start again going to doctors..especially since MCAS is very hard to diagnose aswell...
 

Gingergrrl

Senior Member
Messages
16,171
i don't have ANA, not even close...that's the thing..i kinda suspect MCAS but just don t want to start again going to doctors..especially since MCAS is very hard to diagnose aswell...

I think you guys are using “ANA” to mean two different terms. ANA is the abbreviation for anaphylaxis but it is also the acronym for “anti nuclear antibodies” (general test for autoimmunity) in case this helps.
 

notmyself

Senior Member
Messages
364
I think you guys are using “ANA” to mean two different terms. ANA is the abbreviation for anaphylaxis but it is also the acronym for “anti nuclear antibodies” (general test for autoimmunity) in case this helps.
yes..i meant the anti nuclear antibodies..wich i test twice for them and come back negative ...as for anaphylaxis ,is a hallmark of mcas or not?..thanks
 

Lisa108

Senior Member
Messages
675
I meant antinuclear autoantibodies, too. As for information about MCAS I only know a Swiss homepage (English translation available). Don't know it this is helpful, but here is the link.
 

Gingergrrl

Senior Member
Messages
16,171
Sorry for my confusion @notmyself and when you said you didn’t have ANA, I thought you might’ve been referring to anaphylaxis. Sorry I misunderstood!