@Tunguska
This is your interpretation i am afraid. Since 2015, i am discussing about a
common basis that these syndromes may potentially have (hypothesis) and not for all or some of these syndromes being the same.
It also appears to me that you are confident on what really is behind CFS and PFS : If you know then please make a statement about it.
Again, i do not suggest that these syndromes are the same, i suggest that they have a common basis. I really cannot say anything more if you repeatedly fail to understand the difference.
Nevertheless, could you comment -
especially since you also took Accutane!- on the same topics i pointed to
@Valentijn in this post ?
http://forums.phoenixrising.me/inde...sted-research-on-cfs.51283/page-2#post-852531
Sorry I don't have the time I'd like to do this during the week anymore. 2015 is obsolete, my description of CFS/ME is simply Dr. Davis's findings together with Naviaux, Fluge Mella and analysis from 2016-17 and sticking to the most observable parameters only. The latest PFS findings are from April 2017:
http://www.pfsfoundation.org/news/p...fs-patients-severe-ed-new-study-demonstrates/ Some of the most important links and observations are not on propeciahelp but buried in this long thread:
https://raypeatforum.com/community/...r-and-post-finasteride-syndrome.16194/page-24 and other parts of that forum where PFS sufferers have flocked.
Don't you find it curious how there are almost no PFS sufferers reporting on this CFS/ME forum? The only guy I remember who recently posted and attributed his severe symptoms in part to PFS clearly stated he doesn't think he has CFS/ME. Even self-reported they instinctively diverge.
I counted maybe 5 people posting here who took accutane including myself, but I can tell you, I never at any point had any sexual side effects nor most the one attributed to PFS. Accutane produces a heterogenic sufferer population, such that I have nothing in common with half the sufferers posting on the acne forums. They read PhoenixRising frequently but unfortunately they get nowhere and get sidetracked by the methylation stuff. Retinoic acid is simply one of the most powerful and complicated natural substances in the body and without real research understanding it and most of all giving a good interpretation of its roles, they're basically screwed. To make matters worse, the persistence syndrome may have nothing to do with retinoic acid, and 13-cis has some unique effects from retinoic acid.
I know your ideas were about ER stress and liver. But there's no one and no research placing that much relevance to ER stress in these diseases as a cause of persistence. It blends together with excess ROS in acute drug reactions - absolutely - but there isn't very much linking it to maintaining persistence syndromes. Improving liver is very important to disease management in a lot of these cases, but it's not identifying so far.
Anyhow, I'm going nowhere with this and out of time. What I really want to say, is building a model on the premise these disease share a common basis is simply an error, especially now. If you're doing disease management like I am, then common effects are exactly what to look at to find solutions, but as far as I can tell, you're trying to build a tool to help discover causes and cures. This makes no sense to me, sorry.