LYME SCI: A test to find many infections at once is on the horizon

Judee

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https://www.lymedisease.org/multiplex-test-on-horizon/

Research led by Ricardo Maggi, Ed Breitschwerdt, and colleagues has led to the development of a new test utilizing a multiplex droplet digital PCR “BBB ddPCR” that can simultaneously detect the three B’s—Babesia, Bartonella and Borrelia from both the Lyme and relapsing fever complex. (Maggi et al., 2021)

The standard test combination also misses 89% of early infection (false-negatives), cannot detect all strains of disease-causing Borrelia, and suffers from cross-reactivity with other infectious diseases leading to false-positives. (Steere et al., 2008; Cook, Puri, 2016)

“The ability to co-amplify multiple vector-borne pathogens within a single sample with high sensitivity will greatly enhance the efficiency and efficacy of clinical diagnostic testing, particularly of volume-limited or otherwise hard to obtain sample matrices,” the authors state.
 
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