pattismith
Senior Member
- Messages
- 3,988
I have daily loose stool since I started iron supplementation 11 month ago.
Within two days of Minocycline antibiotic, I realized this issue was suddenly totally fixed, without any change in my diet or supplementation.
I take probiotic bifidobacterium Longum for some weeks but didn't see any difference before starting minocycline.
I found this 2011 study about effect of Minocycline in colitis, I don't know if it's related to my own experience though:
Oral iron exacerbates colitis and influences the intestinal microbiome - PMC (nih.gov)
Within two days of Minocycline antibiotic, I realized this issue was suddenly totally fixed, without any change in my diet or supplementation.
I take probiotic bifidobacterium Longum for some weeks but didn't see any difference before starting minocycline.
I found this 2011 study about effect of Minocycline in colitis, I don't know if it's related to my own experience though:
The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties - ScienceDirect
The results revealed that minocycline exerted an intestinal anti-inflammatory effect when administered as a curative treatment in the TNBS model, modulating both immune and microbiological parameters, being confirmed in the DSS model; whereas none of the other antibiotics tested (tetracycline and metronidazole) showed anti-inflammatory effect.
StudiesTrusted Source show iron supplements can worsen inflammation in the digestive tract. This makes Crohn’s disease and ulcerative colitis symptoms worse.
Iron supplements can cause digestive side effects, including cramping, nausea, diarrhea, and constipation, even if you’re in remission.
Ulcerative Colitis, Crohn’s, and Anemia: What's the Link? (healthline.com)
Oral iron exacerbates colitis and influences the intestinal microbiome - PMC (nih.gov)