Looking for Scientific Article r.e ELISA

[the_phscale]

Its commonly accepted among those of us who have a Lyme diagnosis that the ELISA is an imprecise exam with a high rate of false negatives. I’m trying to find some scientific articles demonstrating this false negative rate to send to a new doc who...frankly, knows a lot less about Lyme than I do . Does anyone have the links, the titles of articles, journals where things were published, dates of publishing...anything to help me narrow my search!

 

[Learner1]

I'm not an expert, but just found these by Googling:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391870/

https://www.hopkinsarthritis.org/arthritis-info/lyme-disease/lyme-disease-diagnosis/

https://www.statnews.com/2017/06/28/early-lyme-tests/

http://blog.questdiagnostics.com/2018/05/lyme-disease-test-negative-what-then/

https://www.cdc.gov/lyme/faq/index.html

https://globallymealliance.org/about-lyme/diagnosis/testing/

Also, the attached does not prove your point, but you should be aware it exists, in case its where your doctor is getting his info. Halperin is associated with IDSA...

Good luck!

 

[the_phscale]

Thank you! This is a great start! Out of curiosity, what were your search terms? I did a google with just “Elisa blood test false negative”, “b burgderfori ab tot reliability rate”, other stuff like that, and I found it really hard to weed through the results.

 

[Art Vandelay]

@duncan may be able to help?

 

[Learner1]

Thank you! This is a great start! Out of curiosity, what were your search terms? I did a google with just “Elisa blood test false negative”, “b burgderfori ab tot reliability rate”, other stuff like that, and I found it really hard to weed through the results.

I believe I did "Lyme Elisa false negative".

Best wishes...

 

[duncan]

I would go to Lymenet Europe and under "Information" you can scroll down and find tons of insight on ELISA and WB.

Better yet. look up anything on the C6 circa 1999 or 2000 and they use the ELISA and WB as benchmarks against which to measure the C6.