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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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This resulted in a 256-peptide immunosignature with the ability to separate ME/CFS cases from controls in the international data sets. We were able to identify a 256-peptide signature that separates ME/CFS samples from healthy controls, suggesting that the hit-and-run hypothesis of immune dysfunction merits further investigation.
By extending testing of both our signature and one previously reported in the literature to larger cohorts, and further interrogating the specific peptides we and others have identified, we may deepen our understanding of the origins of ME/CFS and work towards a clinically meaningful diagnostic biomarker.
Thank you @Hufsamor for posting such an important article.
DoneThank you @Hufsamor for posting such an important article.
For those referencing, might you consider expanding the title to: "Latest from Fluge and Mella: ME/CFS Immunosignature Identified" or something similar?
Stupid question... But what is 256 Peptide? Can anyone explain the results in "laymen terms" lol
Stupid question... But what is 256 Peptide? Can anyone explain the results in "laymen terms" lol