Tis one is only 1/2 as long as the other one!
![Stick Out Tongue :p :p](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
Thank you Thor!
Can anyone proof this, please. I can't read any of these, not even teh ones I type.
Also, I don't know how things like trials should be written. Is it "Phase 1" or "phase 1" or "phase one" or Phase One"? I have no clue.
Also, English does not seem to be a language with which I have any familiarity. So... gleisyt wofen shlurrping.
thanks!
OH! Yeah! Phase I, Phase II, Phase III! That's it! Thanks Kati!
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Question: If you were going to guess on a timetable for, number one, for the test, when they would have a good test? And, number two, when you would think they’re going to have a drug that’s going to help the symptoms? If you were going to guess right now, what do you think the timetable is?
Nancy Klimas: Well, number one is easy, I think number one will come very quickly.
Question: I think six months…
Nancy Klimas: Yeah, I think six months is possible.
Question: What about drug therapy/treatment?
Nancy Klimas: How fast could you do a Phase I, a Phase II and a Phase III? And, if we’re considered “orphan”, which is the big if, Phase IIs can, in the “orphan” world, be something called “a II slash III” [a II/III]. You can start it as a small study and, if it’s looking good, you can just roll it right on into the Phase III. You can keep on going. And, the FDA typically requires two Phase III studies for a drug approval - two years, three years? It could be very quick.
Question: When I fly from north to south, it seems that I really crash afterwards, I find it really hard to recover from that.
Nancy Klimas: You guys are about a litre short in blood volume, ok? If I’m sitting at five litres, you’re sitting at four. So, you’re really, really sensitive to blood volume changes. If you’re a little dry, you crash. You’ve got to hydrate so aggressively when you’re in dry areas.
Question: Unfortunately, I’m not one of your patients. I’ve tried for many years to get in but…
Nancy Klimas: This tells you how terrible this is: I have a 350 patient waiting list. Ok, and there’s no place else. And, I can’t practice… I mean, there’s no way to do it all. That’s why, with the help of Hanna, we were putting together this clinic. A model clinic open in Kendal – we’re going to have our opening in December. But the point of it is…
Question: Can I ask something else?
Nancy Klimas: Yeah, sure.
Question: Some of us may not be able to afford the clinic. That’s a concern for me.
Nancy Klimas: Right, that’s why we’re growing the University of Miami clinic at the same time. I’ll just say, I wish I could solve this problem for everybody. But, at the University of Miami we have very generous patients who donated a salary line for a physician to do nothing but Chronic Fatigue Syndrome. Which is amazing! It’s taken us a little while but we have the doctor hired. She’s going to start in January and we will more than quadruple the volume of our clinic here at the University of Miami which takes all insurance.
Question: How can we get into research…
Nancy Klimas: Oh, you don’t need to be a patient to be in a study. Studies are for everybody and you don’t pay to be in a study, in fact, often the study pays for you.
Let me talk about research for a moment. This tele-health study is a really cool study. It’s the brainchild of years and years of research where we found that Cognitive Behavioural Therapy can really help people take control of their lives. The first studies we did were group therapy here and you had to get here and some of our patients were too sick to get here. And, we didn’t know whether or not we could generalize and say: Yeah, it’s great for everybody. So, we designed this other study and, at home, you take the group on the phone, it’s a tele-health - they give you this phone and fix you up with a group and there’s a Cognitive Behavioural Therapy group on the phone. It’s very neat.
We also have the “Good Day/Bad Day” study I referred to before. I don’t know who’s here from my group besides Mack, here. We still have room for, I think, 70 more patients in that study – lots of room. That’s a neat study because we’re trying to develop bio-markers and we see people four times and we do these very expensive and comprehensive evaluations with all kinds of immune and other kinds of lab tests - they’re all yours, free, they pay you $20 to come.
We have the Gulf War Illness study that has a Chronic Fatigue Syndrome group. And, that is a genomic study.
So, the point of our group here at the University of Miami has always been to advance the science. To advance the science, we have to have study subjects and, frankly, my original reason why I had a clinic was so that somebody was taking care of people so that I could recruit my studies. But, then I got sucked in by you all and I love being your doctor.