Nice thinking out of the box, Violetta. Yes, Magnesium can’t just be by itself as a molecule, it has to be bound to something else to be stable. The biggest difference in different magnesium products is not from the magnesium itself (which is all the same) but from the molecule its bonded to. If you are taking your magnesium in a form where the bond is hard to break such as Magnesium Oxide, then you might as well be taking nothing at all because most will just pass right through you. In other words, it is like there is crazy glue holding the magnesium to its carrier, and if your body can't break the bond, then you won't absorb much if any. Magnesium taurate is mentioned as a good choice of magnesium supplement for people with cardiovascular issues, since it is known to prevent arrhythmias and guard the heart from damage caused by heart attacks. Taurine helps the heart pump blood throughout the body, improves blood flow to the heart and protects the heart from damage due to poor blood flow. As a result, these two compounds, taken in combination as magnesium taurate, could interact to help protect more against cardiovascular disease. Malate is normally good for those with fatigue since malic acid -- a natural fruit acid present in most cells in the body -- is a vital component of enzymes that play a key role in ATP synthesis and energy production. However those with CFS we are learning may not properly make energy through the krebs cycle. Bisglycinate/Glycinate are popular to fix deficiencies due to its lower laxative effect and the glycine might help with anxiety and works well even with low stomach acid but may have issues in those with glutamate balance. Since citric acid is a mild laxative, magnesium citrate functions as a constipation aid as well as a magnesium source. Magnesium L-Threonate is Magnesium supplementation has been shown to help lower blood pressure and reduce the risk of developing diabetes and atherosclerosis. Magnesium L-Threonate is a good oral source of magnesium for brain health, used often for ptsd, anxiety, depression, brain injuries. Elevated levels of magnesium may also protect from irregular heartbeats and sudden cardiac death. As you can see, its the benefits of what the magnesium is attached to that might add additional benefits.
As far as topical going back to the question. Malabsorption is a factor for magnesium deficiency. Magnesium is absorbed in the small intestine and in the colon; so those with intestinal or colon damage such as Crohn’s disease, irritable bowel syndrome, celiac disease, gastroenteritis, idiopathic steatorrhoea, resection of the small intestine, ileostomy patients or patients with ulcerative colitis, or autism may have magnesium deficiency due to this. A high calcium level also impairs magnesium absorption. In these situations, the epsom salt or a Magnesium Chloride transdermal spray therefore may be helpful by bypassing the gut absorption problems. Despite its name, Magnesium oil is not actually an oil - the name originated because of the oily texture when magnesium chloride flakes are mixed with water. Perhaps best from zechstein sea sources which are hidden deep beneath the earth's surface which should naturally be unspoiled by the modern day pollution of heavy metals that unfortunately might be found in some magnesium from other sources.
Chloride is essential to energy production in the body. On a blood test, the optimal range for chloride is 100-106 mEq/L. The Na-K-Cl (Sodium, Potassium, Chloride) system moves sodium, potassium, and chloride ions across the cell membrane barrier into the cell. The number of chloride ions moved equals the sum of the number of sodium and potassium ions, in other words the ratio of ions moved is 1 Sodium:1 Potassium: 2 Chloride. K-Cl (Potassium) cotransport is the electroneutral movement of one K+ (Potassium) ion with one Cl- (Chloride) ion across the cell membrane.
What this means is that you normally need chloride too, and one good way to get some is to take some of your daily magnesium supplement in the chloride form. Chloride is also part of salt such as healthy pink himalayan salt but that will increase your sodium as well. However those with CFS again may need to learn if that is helpful compared to those without CFS.
