Ok, here is my issue.
Like many of you, I have exertional intolerance. Mine is usually presented not as fatigue though, but as pain. I can go swimming for a little bit and be fine. However, I can extrapolate on intensity and experience post-exertional pain, tingling, petechiae, etc. That will take a little bit to recover from. It seems to affect mostly my legs, but I would not say symptoms are limited to that.
I think I have peripheral issues with the oxygen delivery, no sign of pulmonary or heart issue. Also, that seems to be the common theme among Covid long haulers: https://journal.chestnet.org/article/S0012-3692(21)03635-7/fulltext
I read all about Dr. Systrom and the iCPET. I think that should have been the gold standard for exercise intolerance, but unfortunately it isn't, so it is not something it is widely available outside his practice. I also do not have $20k+ laying around to travel abroad to US and get it soon (and they are also probably pretty backed up anyway).
I could probably get a regular CPET locally, if I wait. Then check the lactate levels, which should help to some extent.
But I would like something that would help me on a day-to-day basis, and could somehow objectively help me measure it, and also experiment with certain compounds. I want to know if Mestinon, Midrodine, etc. could increase that limit without risking further damage. When I happen to cross it, it is usually already too late. I do get some signs though.
There is a sensor called Moxy (https://www.moxymonitor.com/) that seems to try to do that, but I haven't heard of any reviews from the ME/CFS community. It tries to measure the SmO2, which is a metric used to measure oxygen delivery to the muscles. It is supposed to check if you are crossing the lactate threshold without having to go to a lab for that. I believe it is targeted for athletes that are trying to pace during endurance competitions.
I have no idea how reliable it is though. It seems pricey, but honestly, if it actually works, it is cheaper than the alternative, given that you can keep reusing it.
Like many of you, I have exertional intolerance. Mine is usually presented not as fatigue though, but as pain. I can go swimming for a little bit and be fine. However, I can extrapolate on intensity and experience post-exertional pain, tingling, petechiae, etc. That will take a little bit to recover from. It seems to affect mostly my legs, but I would not say symptoms are limited to that.
I think I have peripheral issues with the oxygen delivery, no sign of pulmonary or heart issue. Also, that seems to be the common theme among Covid long haulers: https://journal.chestnet.org/article/S0012-3692(21)03635-7/fulltext
I read all about Dr. Systrom and the iCPET. I think that should have been the gold standard for exercise intolerance, but unfortunately it isn't, so it is not something it is widely available outside his practice. I also do not have $20k+ laying around to travel abroad to US and get it soon (and they are also probably pretty backed up anyway).
I could probably get a regular CPET locally, if I wait. Then check the lactate levels, which should help to some extent.
But I would like something that would help me on a day-to-day basis, and could somehow objectively help me measure it, and also experiment with certain compounds. I want to know if Mestinon, Midrodine, etc. could increase that limit without risking further damage. When I happen to cross it, it is usually already too late. I do get some signs though.
There is a sensor called Moxy (https://www.moxymonitor.com/) that seems to try to do that, but I haven't heard of any reviews from the ME/CFS community. It tries to measure the SmO2, which is a metric used to measure oxygen delivery to the muscles. It is supposed to check if you are crossing the lactate threshold without having to go to a lab for that. I believe it is targeted for athletes that are trying to pace during endurance competitions.
I have no idea how reliable it is though. It seems pricey, but honestly, if it actually works, it is cheaper than the alternative, given that you can keep reusing it.