Lactate: the ugly duckling of energy metabolism
Rabinowitz JD, Enerbäck S
Lactate, perhaps the best-known metabolic waste product, was first isolated from sour milk, in which it is produced by lactobacilli. Whereas microbes also generate other fermentation products, such as ethanol or acetone...
Ok, here is my issue.
Like many of you, I have exertional intolerance. Mine is usually presented not as fatigue though, but as pain. I can go swimming for a little bit and be fine. However, I can extrapolate on intensity and experience post-exertional pain, tingling, petechiae, etc. That will...
The RBC-NOX hypothesis
Hello again, everyone. Welcome, to the RBC-NOX hypothesis, which I consider by far my best idea yet.
It connects the IDO metabolic trap, red blood cell deformability, craniocervical instability (including recoveries after surgery), Alan Light’s research on fatigue...